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Literature DB >> 10961457

Regulation of competence for genetic transformation in Streptococcus pneumoniae: a link between quorum sensing and DNA processing genes.

Abstract

Competence for genetic transformation in pneumococcus depends on the coordinated functioning of a dispersed regulon responsible for production of proteins active in DNA binding, uptake, and recombination. This regulon is characterized by a shared noncanonical promoter consensus, TACGAATA, and is capable of 100-fold expression modulations. This review discusses recent evidence that its regulation depends on a novel sigma factor, itself controlled by an autostimulatory quorum sensing system that acts through an extracellular peptide signal.

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Year: 2000 PMID： 10961457 DOI： 10.1016/s0923-2508(00)00171-6

Source DB: PubMed Journal: Res Microbiol ISSN： 0923-2508 Impact factor: 3.992

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Cited

25 in total

Review 1. Stress-induced evolution and the biosafety of genetically modified microorganisms released into the environment.

Authors: V V Velkov
Journal: J Biosci Date: 2001-12 Impact factor: 1.826

2. A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues.

Authors: Carlos Hidalgo-Grass; Inbal Mishalian; Mary Dan-Goor; Ilia Belotserkovsky; Yoni Eran; Victor Nizet; Amnon Peled; Emanuel Hanski
Journal: EMBO J Date: 2006-09-14 Impact factor: 11.598

Review 3. Decoding microbial chatter: cell-cell communication in bacteria.

Authors: Karen L Visick; Clay Fuqua
Journal: J Bacteriol Date: 2005-08 Impact factor: 3.490

Review 4. Bacterial plurality as a general mechanism driving persistence in chronic infections.

Authors: Garth D Ehrlich; Fen Ze Hu; Kai Shen; Paul Stoodley; J Christopher Post
Journal: Clin Orthop Relat Res Date: 2005-08 Impact factor: 4.176

5. Genetic diversity of competence gene loci in clinical genotypes of Streptococcus mutans.

Authors: Marlise I Klein; Sungyon Bang; Flávia M Flório; José Francisco Höfling; Reginaldo B Gonçalves; Daniel J Smith; Renata O Mattos-Graner
Journal: J Clin Microbiol Date: 2006-08 Impact factor: 5.948

6. LuxS involvement in the regulation of genes coding for hemin and iron acquisition systems in Porphyromonas gingivalis.

Authors: Chloe E James; Yoshiaki Hasegawa; Yoonsuk Park; Vincent Yeung; Gena D Tribble; Masae Kuboniwa; Donald R Demuth; Richard J Lamont
Journal: Infect Immun Date: 2006-07 Impact factor: 3.441

Regulation of competence for genetic transformation in Streptococcus pneumoniae: a link between quorum sensing and DNA processing genes.

Review 1. Stress-induced evolution and the biosafety of genetically modified microorganisms released into the environment.

2. A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues.

Review 3. Decoding microbial chatter: cell-cell communication in bacteria.

Review 4. Bacterial plurality as a general mechanism driving persistence in chronic infections.

5. Genetic diversity of competence gene loci in clinical genotypes of Streptococcus mutans.

6. LuxS involvement in the regulation of genes coding for hemin and iron acquisition systems in Porphyromonas gingivalis.

7. The pneumococcal σ^X activator, ComW, is a DNA-binding protein critical for natural transformation.

8. Generic metric to quantify quorum sensing activation dynamics.

9. Characterization of competence and biofilm development of a Streptococcus sanguinis endocarditis isolate.

Review 10. The cell pole: the site of cross talk between the DNA uptake and genetic recombination machinery.

Regulation of competence for genetic transformation in Streptococcus pneumoniae: a link between quorum sensing and DNA processing genes.

Review 1. Stress-induced evolution and the biosafety of genetically modified microorganisms released into the environment.

2. A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues.

Review 3. Decoding microbial chatter: cell-cell communication in bacteria.

Review 4. Bacterial plurality as a general mechanism driving persistence in chronic infections.

5. Genetic diversity of competence gene loci in clinical genotypes of Streptococcus mutans.

6. LuxS involvement in the regulation of genes coding for hemin and iron acquisition systems in Porphyromonas gingivalis.

7. The pneumococcal σX activator, ComW, is a DNA-binding protein critical for natural transformation.

8. Generic metric to quantify quorum sensing activation dynamics.

9. Characterization of competence and biofilm development of a Streptococcus sanguinis endocarditis isolate.

Review 10. The cell pole: the site of cross talk between the DNA uptake and genetic recombination machinery.

7. The pneumococcal σ^X activator, ComW, is a DNA-binding protein critical for natural transformation.