Literature DB >> 10960767

Detection of mammaglobin expressing cells in blood of breast cancer patients.

B Suchy1, F Austrup, G Driesel, C Eder, I Kusiak, P Uciechowski, H J Grill, M Giesing.   

Abstract

Expression of human mammaglobin (hMAM) was published to be exclusively expressed in mammary tissue, in solid tumors, axillary lymph nodes and disseminated cancer cells in blood of breast cancer patients. A quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) test was applied to investigate hMAM expression in blood of breast cancer patients. Mammaglobin mRNA expression was found not only in breast cancer cell lines but also in cell lines of other cancer origin. In our patient cohort hMAM expression in 11/98 (11%) samples of breast cancer and 3/12 (25%) ovarian cancer patients could be detected. hMAM mRNA expression as a candidate marker for the detection of disseminated cancer cells in blood of breast cancer patients showed low sensitivity and reduced tissue specificity. A prognostic significance of hMAM expression could not be demonstrated.

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Year:  2000        PMID： 10960767     DOI： 10.1016/s0304-3835(00)00520-6

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  10 in total

Review 1.  The detection of circulating breast cancer cells in blood.

Authors:  A M Gilbey; D Burnett; R E Coleman; I Holen
Journal:  J Clin Pathol       Date:  2004-09       Impact factor: 3.411

2.  Mammaglobin as a novel breast cancer biomarker: multigene reverse transcription-PCR assay and sandwich ELISA.

Authors:  Barbara K Zehentner; David H Persing; Amadou Deme; Papa Toure; Stephen E Hawes; Lisa Brooks; Qinghua Feng; Dawn C Hayes; Cathy W Critichlow; Raymond L Houghton; Nancy B Kiviat
Journal:  Clin Chem       Date:  2004-09-16       Impact factor: 8.327

3.  Increase in number of circulating disseminated epithelial cells after surgery for non-small cell lung cancer monitored by MAINTRAC(R) is a predictor for relapse: A preliminary report.

Authors:  Axel Rolle; Rainer Günzel; Ulrich Pachmann; Babette Willen; Klaus Höffken; Katharina Pachmann
Journal:  World J Surg Oncol       Date:  2005-03-31       Impact factor: 2.754

4.  Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes: possible relevance to the assays for the detection of micrometastatic breast cancer.

Authors:  A Ballestrero; A Garuti; M Bertolotto; I Rocco; D Boy; A Nencioni; L Ottonello; F Patrone
Journal:  Br J Cancer       Date:  2005-05-23       Impact factor: 7.640

Review 5.  Human mammaglobin in breast cancer: a brief review of its clinical utility.

Authors:  Fawwaz Shakir Al Joudi
Journal:  Indian J Med Res       Date:  2014-05       Impact factor: 2.375

6.  Circulating tumour cell detection: a direct comparison between the CellSearch System, the AdnaTest and CK-19/mammaglobin RT-PCR in patients with metastatic breast cancer.

Authors:  I Van der Auwera; D Peeters; I H Benoy; H J Elst; S J Van Laere; A Prové; H Maes; P Huget; P van Dam; P B Vermeulen; L Y Dirix
Journal:  Br J Cancer       Date:  2009-12-01       Impact factor: 7.640

7.  Real-time RT-PCR correlates with immunocytochemistry for the detection of disseminated epithelial cells in bone marrow aspirates of patients with breast cancer.

Authors:  I H Benoy; H Elst; I Van der Auwera; S Van Laere; P van Dam; E Van Marck; S Scharpé; P B Vermeulen; L Y Dirix
Journal:  Br J Cancer       Date:  2004-11-15       Impact factor: 7.640

8.  Real-time RT-PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulating tumour cells in patients with breast cancer.

Authors:  I H Benoy; H Elst; M Philips; H Wuyts; P Van Dam; S Scharpé; E Van Marck; P B Vermeulen; L Y Dirix
Journal:  Br J Cancer       Date:  2006-03-13       Impact factor: 7.640

9.  The expression of CK-19 gene in circulating tumor cells of blood samples of metastatic breast cancer women.

Authors:  Setareh Soltani; Fariborz Mokarian; Mojtaba Panjehpour
Journal:  Res Pharm Sci       Date:  2015 Nov-Dec

10.  Over-expression of mammaglobin-B in canine mammary tumors.

Authors:  Mamta Pandey; B V Sunil Kumar; Kuldip Gupta; Ram Saran Sethi; Ashwani Kumar; Ramneek Verma
Journal:  BMC Vet Res       Date:  2018-06-15       Impact factor: 2.741
  10 in total

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