| Literature DB >> 10960677 |
Abstract
We investigated the effects of diesel exhaust particulates on the human allergic response using in vivo human nasal challenges. Diesel particles and phenanthrene, one of their constituent polyaromatic hydrocarbons, were shown to enhance total allergic antibody (IgE) production, enhance allergen-specific IgE in the presence of allergen, and induce sensitization to a neoantigen.Entities:
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Year: 2000 PMID: 10960677 DOI: 10.1016/s0162-3109(00)00234-4
Source DB: PubMed Journal: Immunopharmacology ISSN: 0162-3109