Literature DB >> 10956205

Identification of a chemical tool for the orphan nuclear receptor FXR.

P R Maloney1, D J Parks, C D Haffner, A M Fivush, G Chandra, K D Plunket, K L Creech, L B Moore, J G Wilson, M C Lewis, S A Jones, T M Willson.   

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Year:  2000        PMID： 10956205     DOI： 10.1021/jm0002127

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  149 in total

1.  Activation of the farnesoid X receptor induces hepatic expression and secretion of fibroblast growth factor 21.

Authors:  Holly A Cyphert; Xuemei Ge; Alison B Kohan; Lisa M Salati; Yanqiao Zhang; F Bradley Hillgartner
Journal:  J Biol Chem       Date:  2012-06-01       Impact factor: 5.157

2.  A novel heterozygous NR1H4 termination codon mutation in idiopathic infantile cholestasis.

Authors:  Xiu-Qi Chen; Lin-Lin Wang; Qing-Wen Shan; Qing Tang; Ya-Nan Deng; Shu-Jun Lian; Xiang Yun
Journal:  World J Pediatr       Date:  2011-06-01       Impact factor: 2.764

3.  Roles of microRNA-29a in the antifibrotic effect of farnesoid X receptor in hepatic stellate cells.

Authors:  Jiang Li; Yifei Zhang; Ramalinga Kuruba; Xiang Gao; Chandrashekhar R Gandhi; Wen Xie; Song Li
Journal:  Mol Pharmacol       Date:  2011-04-21       Impact factor: 4.436

4.  Analysis of selection methodologies for combinatorial library design.

Authors:  Rosalia Pascual; José I Borrell; Jordi Teixidó
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

5.  Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro.

Authors:  Deanna L Howarth; Lee R Hagey; Sheran H W Law; Ni Ai; Matthew D Krasowski; Sean Ekins; John T Moore; Erin M Kollitz; David E Hinton; Seth W Kullman
Journal:  Aquat Toxicol       Date:  2010-03-01       Impact factor: 4.964

6.  Inhibitory effects of bile acids and synthetic farnesoid X receptor agonists on rotavirus replication.

Authors:  Yunjeong Kim; Kyeong-Ok Chang
Journal:  J Virol       Date:  2011-09-28       Impact factor: 5.103

Review 7.  Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism.

Authors:  Timothy S Tracy; Amarjit S Chaudhry; Bhagwat Prasad; Kenneth E Thummel; Erin G Schuetz; Xiao-Bo Zhong; Yun-Chen Tien; Hyunyoung Jeong; Xian Pan; Laura M Shireman; Jessica Tay-Sontheimer; Yvonne S Lin
Journal:  Drug Metab Dispos       Date:  2015-12-17       Impact factor: 3.922

8.  Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice.

Authors:  Helen B Hartman; Stephen J Gardell; Chris J Petucci; Shuguang Wang; Julie A Krueger; Mark J Evans
Journal:  J Lipid Res       Date:  2009-01-27       Impact factor: 5.922

9.  Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor.

Authors:  Donna D Yu; Wenwei Lin; Barry M Forman; Taosheng Chen
Journal:  Bioorg Med Chem       Date:  2014-04-16       Impact factor: 3.641

Review 10.  The Farnesoid X Receptor (FXR) as modulator of bile acid metabolism.

Authors:  Folkert Kuipers; Thierry Claudel; Ekkehard Sturm; Bart Staels
Journal:  Rev Endocr Metab Disord       Date:  2004-12       Impact factor: 6.514
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