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Literature DB >> 10952584

Comparative In vitro activities of ertapenem (MK-0826) against 1,001 anaerobes isolated from human intra-abdominal infections.

E J Goldstein¹, D M Citron, C Vreni Merriam, Y Warren, K L Tyrrell.

Abstract

By using an agar dilution method, the comparative in vitro activities of ertapenem (MK-0826) were studied against 1,001 anaerobes isolated from human intra-abdominal infections in 17 countries worldwide. MK-0826 was uniformly active against all isolates, including all Bacteroides fragilis group species isolates, with the exception of 12 of 61 (20%) strains of Bilophila wadsworthia, 3 strains of lactobacilli, and 1 isolate of Acidaminococcus fermentans. Geographical variation in activity was not observed.

Entities: Chemical Disease Species

Mesh：

Substances：
Carbapenems
L 749345

Year: 2000 PMID： 10952584 PMCID： PMC90074 DOI： 10.1128/AAC.44.9.2389-2394.2000

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

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Journal: J Antimicrob Chemother Date: 1999-05 Impact factor: 5.790

2. In vitro activities of the potent, broad-spectrum carbapenem MK-0826 (L-749,345) against broad-spectrum beta-lactamase-and extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli clinical isolates.

Authors: J Kohler; K L Dorso; K Young; G G Hammond; H Rosen; H Kropp; L L Silver
Journal: Antimicrob Agents Chemother Date: 1999-05 Impact factor: 5.191

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Journal: Antimicrob Agents Chemother Date: 1997-08 Impact factor: 5.191

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Journal: Clin Infect Dis Date: 1995-06 Impact factor: 9.079

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Journal: Lancet Date: 1995-05-20 Impact factor: 79.321

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Journal: Clin Infect Dis Date: 1993-06 Impact factor: 9.079

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Journal: J Antimicrob Chemother Date: 1991-07 Impact factor: 5.790

10. In vivo activity and pharmacokinetic evaluation of a novel long-acting carbapenem antibiotic, MK-826 (L-749,345).

Authors: C J Gill; J J Jackson; L S Gerckens; B A Pelak; R K Thompson; J G Sundelof; H Kropp; H Rosen
Journal: Antimicrob Agents Chemother Date: 1998-08 Impact factor: 5.191

18 in total

1. Comparative in vitro susceptibilities of 396 unusual anaerobic strains to tigecycline and eight other antimicrobial agents.

Authors: Ellie J C Goldstein; Diane M Citron; C Vreni Merriam; Yumi A Warren; Kerin L Tyrrell; Helen T Fernandez
Journal: Antimicrob Agents Chemother Date: 2006-08-28 Impact factor: 5.191

2. Efficacy and safety of ertapenem versus piperacillin-tazobactam for the treatment of intra-abdominal infections requiring surgical intervention.

Authors: Arturo S Dela Pena; Walter Asperger; Ferdinand Köckerling; Raul Raz; Reinhold Kafka; Brian Warren; Malathi Shivaprakash; France Vrijens; Hilde Giezek; Mark J DiNubile; Christina Y Chan
Journal: J Gastrointest Surg Date: 2006-04 Impact factor: 3.452

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Authors: Julius Maina Mathara; Ulrich Schillinger; Phillip M Kutima; Samuel K Mbugua; Claudia Guigas; Charles Franz; Wilhelm H Holzapfel
Journal: Curr Microbiol Date: 2008-01-03 Impact factor: 2.188

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Authors: Mao Mao An; Zui Zou; Hui Shen; Jun Dong Zhang; Meng Li Chen; Ping Liu; Rui Wang; Yuan Ying Jiang
Journal: BMC Infect Dis Date: 2009-12-02 Impact factor: 3.090