Literature DB >> 10939962

Toxicogenomics. Toxicologists brace for genomics revolution.

R A Lovett.   

Abstract

According to researchers who gathered here at a high-powered summit this month, toxicology may be on the verge of changing the way it collects raw data--adopting a process that could reduce animal use and improve test results. The new approach, called "toxicogenomics," uses DNA arrays to profile gene expression in cells exposed to test compounds. But some leaders in the field warn against rushing too quickly to embrace DNA tests, which are still difficult to interpret.

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Year:  2000        PMID: 10939962     DOI: 10.1126/science.289.5479.536

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  4 in total

1.  A bold new direction for environmental health research.

Authors:  K Olden; J Guthrie; S Newton
Journal:  Am J Public Health       Date:  2001-12       Impact factor: 9.308

Review 2.  The genomic revolution: what does it mean for human and ecological risk assessment?

Authors:  Curtis C Travis; William E Bishop; David P Clarke
Journal:  Ecotoxicology       Date:  2003-12       Impact factor: 2.823

3.  Gene-environment interactions in the development of complex disease phenotypes.

Authors:  Rosemarie G Ramos; Kenneth Olden
Journal:  Int J Environ Res Public Health       Date:  2008-03       Impact factor: 3.390

Review 4.  Recent applications of DNA microarray technology to toxicology and ecotoxicology.

Authors:  Teresa Lettieri
Journal:  Environ Health Perspect       Date:  2006-01       Impact factor: 9.031

  4 in total

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