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Literature DB >> 1092612

T cell-dependent mediator in the immune response. III. The role of non-specific factor (NSF) in the in vitro immune response.

Abstract

Evidence is presented which suggests that T cell-dependent nonspecific factor (NSF) cannot be the sole mediator of 'co-operation' for all types of thymus-dependent antibody response. NSF can replace the requirement for T cells in responses to hapten conjugated to particulate carriers, but cannot do so in responses to hapten conjugates of soluble thymus-dependent carriers.

Entities: Gene

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Year: 1975 PMID： 1092612 PMCID： PMC1445774

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

21 in total

1. The carrier effect in the secondary response to hapten-protein conjugates. I. Measurement of the effect with transferred cells and objections to the local environment hypothesis.

Authors: N A Mitchison
Journal: Eur J Immunol Date: 1971-01 Impact factor: 5.532

2. Some physical-chemical properties of chicken gamma-globulins and their pepsin and papain digestion products.

Authors: H S Tenenhouse; H F Deutsch
Journal: Immunochemistry Date: 1966-01

3. Soluble mediators of T-B interaction.

Authors: R H Gisler; F Staber; E Rüde; P Dukor
Journal: Eur J Immunol Date: 1973-10 Impact factor: 5.532

4. Stimulation in vivo and in vitro of anti-dinitrophenyl antibodies with homologous protein carriers devoid of hapten.

Authors: P H Strausbauch; R Tarrab; A Sulica; M Sela
Journal: J Immunol Date: 1972-01 Impact factor: 5.422

5. When allogeneic mouse spleen cells are mixed in vitro the T-cells secrete a product which guides the maturation of B-cells.

Authors: S Britton
Journal: Scand J Immunol Date: 1972 Impact factor: 3.487

6. Carrier specificity and the allogeneic effect in mice.

Authors: K Rajewsky; G E Roelants; B A Askonas
Journal: Eur J Immunol Date: 1972-12 Impact factor: 5.532

7. Immunogenicity of trinitrophenyl-hemocyanin: production of primary and secondary anti-hapten precipitins.

Authors: M B Rittenberg; A A Amkraut
Journal: J Immunol Date: 1966-09 Impact factor: 5.422

8. The allogeneic effect in inbred mice. I. Experimental conditions for the enhancement of hapten-specific secondary antibody responses by the graft-versus-host reaction.

Authors: D P Osborne; D H Katz
Journal: J Exp Med Date: 1972-09-01 Impact factor: 14.307

9. The allogeneic effect in inbred mice. II. Establishment of the cellular interactions required for enhancement of antibody production by the graft-versus-host reaction.

Authors: D H Katz; D P Osborne
Journal: J Exp Med Date: 1972-09-01 Impact factor: 14.307

10. Studies on mouse leukaemia. The role of the thymus in leukaemogenesis by cell-free leukaemic filtrates.

Authors: J F MILLER
Journal: Br J Cancer Date: 1960-03 Impact factor: 7.640

17 in total

1. The inter-relationship of antigenic structure, thymus-independence and adjuvanticity. IV. A general model for B-cell induction.

Authors: H Waldmann; A Munro
Journal: Immunology Date: 1975-03 Impact factor: 7.397

10. Antigen-non-specific T-cell factor in B-cell activation. Origin, biological properties and failure to show a relationship to H-2.

Authors: H Waldmann; P Poulton; C Desaymard
Journal: Immunology Date: 1976-05 Impact factor: 7.397

T cell-dependent mediator in the immune response. III. The role of non-specific factor (NSF) in the in vitro immune response.

1. The carrier effect in the secondary response to hapten-protein conjugates. I. Measurement of the effect with transferred cells and objections to the local environment hypothesis.

2. Some physical-chemical properties of chicken gamma-globulins and their pepsin and papain digestion products.

3. Soluble mediators of T-B interaction.

4. Stimulation in vivo and in vitro of anti-dinitrophenyl antibodies with homologous protein carriers devoid of hapten.

5. When allogeneic mouse spleen cells are mixed in vitro the T-cells secrete a product which guides the maturation of B-cells.

6. Carrier specificity and the allogeneic effect in mice.

7. Immunogenicity of trinitrophenyl-hemocyanin: production of primary and secondary anti-hapten precipitins.

8. The allogeneic effect in inbred mice. I. Experimental conditions for the enhancement of hapten-specific secondary antibody responses by the graft-versus-host reaction.

9. The allogeneic effect in inbred mice. II. Establishment of the cellular interactions required for enhancement of antibody production by the graft-versus-host reaction.

10. Studies on mouse leukaemia. The role of the thymus in leukaemogenesis by cell-free leukaemic filtrates.

1. The inter-relationship of antigenic structure, thymus-independence and adjuvanticity. IV. A general model for B-cell induction.

2. Antibody responses to non-immunogenic synthetic peptides induced by co-immunization with immunogenic peptides.

3. The role of macrophages in the adjuvant effect on antibody production of Corynebacterium parvum.

4. Non-specific factor replaces T cells in an IgG response to soluble antigens.

5. In vitro anamnestic immune responses and modulating factors.

6. Restriction in the function of single helper T cells.

7. The T cell-dependent period of the immune response to sheep erythrocytes.

8. Escape from antibody-mediated immune suppression in vitro by delayed-type hypersensitivity reaction.

9. The 'intrinsic adjuvanticity' and immunogenicity of trinitrophenylated lipopolysaccharide.

10. Antigen-non-specific T-cell factor in B-cell activation. Origin, biological properties and failure to show a relationship to H-2.