Literature DB >> 10919242

[Microfracture for treatment of cartilage detects].

H H Pässler1.   

Abstract

Subchondral bone plate microfracture technique (Steadman) has shown to enhance chondral resurfacing by providing a suitable environment for tissue regeneration and taking advantage of the body's own healing potential. Microfracture technique belongs to the bone marrow stimulating methods like abrasion arthroplasty or subchondral bone drilling. Using a specially designed awl or pick, multiple perforations ("microfractures") are placed 3 to 4 mm apart and about 4 mm deep into the subchondral bone to reach a zone of vascularization. The formation of a fibrin clot ("super clot") containing the desired pluripotential stem cells is stimulated. This clot then differentiates and remodels, resulting in a durable fibrocartilage repair tissue. The arthroscopic awls produce essentially no thermal necrosis of the bone compared to hand-driven or motorized drills. In contrary to drills, it is possible with differently curved awls to reach and treat every area of the knee joint or even of the upper ankle or shoulder joint. Between 1992 and 1998 this technique has been used in 351 cases. 162 patients were interviewed with a questionnaire with respect to their subjective judgement of health between 3 and 6 years (mean 4.4) after operation. Pain was the parameter with the greatest improvement. 78% of the patients improved, 18% remained unchanged and 4% were worse. Microfracture is an advisable option for the treatment of full thickness chondral defects.

Entities:  

Mesh:

Year:  2000        PMID: 10919242

Source DB:  PubMed          Journal:  Zentralbl Chir        ISSN: 0044-409X            Impact factor:   0.942


  8 in total

1.  Reliability of 3D localisation of ACL attachments on MRI: comparison using multi-planar 2D versus high-resolution 3D base sequences.

Authors:  Vimarsha Gopal Swami; June Cheng-Baron; Catherine Hui; Richard B Thompson; Jacob Lester Jaremko
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-03-21       Impact factor: 4.342

Review 2.  Microfracture for the treatment of cartilage defects in the knee joint - A golden standard?

Authors:  Christoph Erggelet; P Vavken
Journal:  J Clin Orthop Trauma       Date:  2016-06-28

Review 3.  Clinical outcome after microfracture of the knee: a meta-analysis of before/after-data of controlled studies.

Authors:  Lukas Negrin; Florian Kutscha-Lissberg; Gerald Gartlehner; Vilmos Vecsei
Journal:  Int Orthop       Date:  2011-10-04       Impact factor: 3.075

4.  [Mid-term results of autologous chondrocyte transplantation in knee and ankle. A one- to six-year follow-up study].

Authors:  R Dorotka; R Kotz; S Trattnig; S Nehrer
Journal:  Z Rheumatol       Date:  2004-10       Impact factor: 1.372

5.  [Microfracture technique for treatment of osteochondral and degenerative chondral lesions of the talus. 2-year results of a prospective study].

Authors:  H Thermann; C Becher
Journal:  Unfallchirurg       Date:  2004-01       Impact factor: 1.000

Review 6.  Advances and Prospects in Stem Cells for Cartilage Regeneration.

Authors:  Mingjie Wang; Zhiguo Yuan; Ning Ma; Chunxiang Hao; Weimin Guo; Gengyi Zou; Yu Zhang; Mingxue Chen; Shuang Gao; Jiang Peng; Aiyuan Wang; Yu Wang; Xiang Sui; Wenjing Xu; Shibi Lu; Shuyun Liu; Quanyi Guo
Journal:  Stem Cells Int       Date:  2017-01-26       Impact factor: 5.443

7.  Chondral defects of the glenohumeral joint: Long-term outcome after microfracturing of the shoulder.

Authors:  Sophia M Hünnebeck; Petra Magosch; Peter Habermeyer; Markus Loew; Sven Lichtenberg
Journal:  Obere Extrem       Date:  2017-06-29

Review 8.  Current Therapeutic Strategies for Stem Cell-Based Cartilage Regeneration.

Authors:  Yoojun Nam; Yeri Alice Rim; Jennifer Lee; Ji Hyeon Ju
Journal:  Stem Cells Int       Date:  2018-03-25       Impact factor: 5.443

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.