| Literature DB >> 1091664 |
R Noyes, S F Brunk, D A Baram, A Canter.
Abstract
A preliminary trial of oral delta-9-tetrahydrocannabinol (THC) demonstrated an analgesic effect of the drug in patients experiencing cancer pain. Placebo and 5, 10, 15, and 20 mg THC were administered double blind to ten patients. Pain relief significantly superior to placebo was demonstrated at high dose levels (15 and 20 mg). At these levels, substantial sedation and mental clouding were reported.Entities:
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Year: 1975 PMID： 1091664 DOI： 10.1002/j.1552-4604.1975.tb02348.x
Source DB: PubMed Journal: J Clin Pharmacol ISSN： 0091-2700 Impact factor: 3.126