Literature DB >> 10915036

Solid phase synthesis of [18F]labelled peptides for positron emission tomography.

J L Sutcliffe-Goulden1, M J O'Doherty, S S Bansal.   

Abstract

A strategy for the solid phase synthesis of [18F]labelled peptides has been developed. The peptides were prepared on solid support and acylated with 4-[18F]fluorobenzoic acid using HATU within 3 min and the labelled peptide was released from the solid support within 7 min. The [18F]labelled peptides were produced in good purity with a specific activity of 20-25 GBq/micromol.

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Year:  2000        PMID： 10915036     DOI： 10.1016/s0960-894x(00)00179-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

1.  Preparation of 18F-labeled peptides using the copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition.

Authors:  Herman S Gill; Jan Marik
Journal:  Nat Protoc       Date:  2011-10-13       Impact factor: 13.491

Review 2.  Radiosyntheses using fluorine-18: the art and science of late stage fluorination.

Authors:  Erin L Cole; Megan N Stewart; Ryan Littich; Raphael Hoareau; Peter J H Scott
Journal:  Curr Top Med Chem       Date:  2014       Impact factor: 3.295

3.  One-step (18)F-labeling of peptides for positron emission tomography imaging using the SiFA methodology.

Authors:  Carmen Wängler; Sabrina Niedermoser; Joshua Chin; Katy Orchowski; Esther Schirrmacher; Klaus Jurkschat; Liuba Iovkova-Berends; Alexey P Kostikov; Ralf Schirrmacher; Björn Wängler
Journal:  Nat Protoc       Date:  2012-10-04       Impact factor: 13.491

4.  New Dioxaborolane Chemistry Enables [(18)F]-Positron-Emitting, Fluorescent [(18)F]-Multimodality Biomolecule Generation from the Solid Phase.

Authors:  Erik A Rodriguez; Ye Wang; Jessica L Crisp; David R Vera; Roger Y Tsien; Richard Ting
Journal:  Bioconjug Chem       Date:  2016-04-27       Impact factor: 4.774

5.  Comparison of three ¹⁸F-labeled carboxylic acids with ¹⁸F-FDG of the differentiation tumor from inflammation in model mice.

Authors:  Hongliang Wang; Ganghua Tang; Kongzhen Hu; Tingting Huang; Xiang Liang; Zhifang Wu; Sijin Li
Journal:  BMC Med Imaging       Date:  2016-01-12       Impact factor: 1.930

6.  Targeting lysyl oxidase for molecular imaging in breast cancer.

Authors:  Melinda Wuest; Manuela Kuchar; Sai Kiran Sharma; Susan Richter; Ingrit Hamann; Monica Wang; Larissa Vos; John R Mackey; Frank Wuest; Reik Löser
Journal:  Breast Cancer Res       Date:  2015-08-13       Impact factor: 6.466
  6 in total

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