Literature DB >> 1091183

The use of haloperidol for treatment of postoperative nausea and vomiting--a double-blind placebo-controlled trial.

M D Barton, M Libonati, P J Cohen.   

Abstract

Sixty-two postoperative patients were admitted to a double-blind study to compare the therapeutic effectiveness of a single intramuscular injection of 1 mg of haloperidol with that of a placebo for the relief of vomiting and nausea following surgical procedures. Significantly fewer patients continued to vomit or experience nausea in the haloperidol-treatment group than in the placebo-treatment group. No statistically or clinically significant change in vital signs occurred in the haloperidol-treatment group. No serious side effect occurred in either group.

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Year:  1975        PMID: 1091183     DOI: 10.1097/00000542-197504000-00028

Source DB:  PubMed          Journal:  Anesthesiology        ISSN: 0003-3022            Impact factor:   7.892


  7 in total

Review 1.  Prevention and treatment of postoperative nausea and vomiting.

Authors:  A L Kovac
Journal:  Drugs       Date:  2000-02       Impact factor: 9.546

2.  Comparison of dexamethasone with ondansetron or haloperidol for prevention of patient-controlled analgesia-related postoperative nausea and vomiting: a randomized clinical trial.

Authors:  Po-Kai Wang; Pei-Jiuan Tsay; Chia-Chun Huang; Hsien-Yong Lai; Pei-Chin Lin; Shen-Jer Huang; Yi Lee
Journal:  World J Surg       Date:  2012-04       Impact factor: 3.352

3.  Antiemetic effect of haloperidol in the dog as related to plasma level and dose.

Authors:  C J Niemegeers; J J Heykants; P A Janssen
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

4.  Comparison of droperidol, haloperidol and prochlorperazine as postoperative anti-emetics.

Authors:  E A Loeser; G Bennett; T H Stanley; R Machin
Journal:  Can Anaesth Soc J       Date:  1979-03

5.  Prophylactic administration of haloperidol plus midazolam reduces postoperative nausea and vomiting better than using each drug alone in patients undergoing middle ear surgery.

Authors:  Azim Honarmand; Mohammadreza Safavi; Gholamreza Khalili; Fatemeh Mohammadnejad
Journal:  Saudi J Anaesth       Date:  2012-04

6.  Systematic review on the recurrence of postoperative nausea and vomiting after a first episode in the recovery room - implications for the treatment of PONV and related clinical trials.

Authors:  Leopold H J Eberhart; Silke Frank; Henning Lange; Astrid M Morin; André Scherag; Hinnerk Wulf; Peter Kranke
Journal:  BMC Anesthesiol       Date:  2006-12-13       Impact factor: 2.217

7.  Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.

Authors:  Stephanie Weibel; Gerta Rücker; Leopold Hj Eberhart; Nathan L Pace; Hannah M Hartl; Olivia L Jordan; Debora Mayer; Manuel Riemer; Maximilian S Schaefer; Diana Raj; Insa Backhaus; Antonia Helf; Tobias Schlesinger; Peter Kienbaum; Peter Kranke
Journal:  Cochrane Database Syst Rev       Date:  2020-10-19
  7 in total

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