Literature DB >> 10903940

Towards the nonstick egg: designing fluorous proteins.

E Neil1, G Marsh.   

Abstract

Anyone who has made scrambled eggs will have had cause to praise the properties of Teflon. Teflon's highly chemically inert and nonstick nature derives from the perfluorinated polymer polytetrafluoroethylene. Perfluorocarbons have unique and valuable physical properties not found in nature. By incorporating fluorine into proteins, it might be possible to produce biological molecules with novel and useful properties.

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Year:  2000        PMID： 10903940     DOI： 10.1016/s1074-5521(00)00139-3

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  20 in total

1.  Structural basis for the enhanced stability of highly fluorinated proteins.

Authors:  Benjamin C Buer; Jennifer L Meagher; Jeanne A Stuckey; E Neil G Marsh
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-12       Impact factor: 11.205

Review 2.  Fluorine: a new element in protein design.

Authors:  Benjamin C Buer; E Neil G Marsh
Journal:  Protein Sci       Date:  2012-02-14       Impact factor: 6.725

3.  2005 Emil Thomas Kaiser Award.

Authors:  Ronald T Raines
Journal:  Protein Sci       Date:  2006-05       Impact factor: 6.725

4.  Comparison of the structures and stabilities of coiled-coil proteins containing hexafluoroleucine and t-butylalanine provides insight into the stabilizing effects of highly fluorinated amino acid side-chains.

Authors:  Benjamin C Buer; Jennifer L Meagher; Jeanne A Stuckey; E Neil G Marsh
Journal:  Protein Sci       Date:  2012-10-01       Impact factor: 6.725

5.  Tag and Capture Flow Hydrogen Exchange Mass Spectrometry with a Fluorous-Immobilized Probe.

Authors:  Sean R Marcsisin; Cary Liptak; Jason Marineau; James E Bradner; John R Engen
Journal:  Anal Chem       Date:  2015-05-29       Impact factor: 6.986

6.  Biosynthesis and stability of coiled-coil peptides containing (2S,4R)-5,5,5-trifluoroleucine and (2S,4S)-5,5,5-trifluoroleucine.

Authors:  Jin Kim Montclare; Soojin Son; Ginevra A Clark; Krishna Kumar; David A Tirrell
Journal:  Chembiochem       Date:  2009-01-05       Impact factor: 3.164

Review 7.  Using chemical approaches to study selenoproteins-focus on thioredoxin reductases.

Authors:  Robert J Hondal
Journal:  Biochim Biophys Acta       Date:  2009-05-04

8.  Comparison of the structural stability and dynamic properties of recombinant anthrax protective antigen and its 2-fluorohistidine-labeled analogue.

Authors:  Lei Hu; Sangeeta B Joshi; Kiran K Andra; Santosh V Thakkar; David B Volkin; James G Bann; C Russell Middaugh
Journal:  J Pharm Sci       Date:  2012-08-21       Impact factor: 3.534

9.  Origin of the stability conferred upon collagen by fluorination.

Authors:  Matthew D Shoulders; Kimberli J Kamer; Ronald T Raines
Journal:  Bioorg Med Chem Lett       Date:  2009-04-21       Impact factor: 2.823

10.  Gallium (III) triflate catalyzed efficient Strecker reaction of ketones and their fluorinated analogs.

Authors:  G K Surya Prakash; Thomas Mathew; Chiradeep Panja; Steevens Alconcel; Habiba Vaghoo; Clement Do; George A Olah
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-28       Impact factor: 11.205
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