Literature DB >> 10903578

Experience-dependent changes in cerebral activation during human REM sleep.

P Maquet1, S Laureys, P Peigneux, S Fuchs, C Petiau, C Phillips, J Aerts, G Del Fiore, C Degueldre, T Meulemans, A Luxen, G Franck, M Van Der Linden, C Smith, A Cleeremans.   

Abstract

The function of rapid-eye-movement (REM) sleep is still unknown. One prevailing hypothesis suggests that REM sleep is important in processing memory traces. Here, using positron emission tomography (PET) and regional cerebral blood flow measurements, we show that waking experience influences regional brain activity during subsequent sleep. Several brain areas activated during the execution of a serial reaction time task during wakefulness were significantly more active during REM sleep in subjects previously trained on the task than in non-trained subjects. These results support the hypothesis that memory traces are processed during REM sleep in humans.

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Year:  2000        PMID: 10903578     DOI: 10.1038/77744

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN: 1097-6256            Impact factor:   24.884


  153 in total

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