Literature DB >> 10903565

A time-less function for mouse timeless.

A L Gotter1, T Manganaro, D R Weaver, L F Kolakowski, B Possidente, S Sriram, D T MacLaughlin, S M Reppert.   

Abstract

The timeless (tim) gene is essential for circadian clock function in Drosophila melanogaster. A putative mouse homolog, mTimeless (mTim), has been difficult to place in the circadian clock of mammals. Here we show that mTim is essential for embryonic development, but does not have substantiated circadian function.

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Year:  2000        PMID： 10903565     DOI： 10.1038/77653

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


  45 in total

Review 1.  Flies, clocks and evolution.

Authors:  E Rosato; C P Kyriacou
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2001-11-29       Impact factor: 6.237

2.  TIMELESS mutation alters phase responsiveness and causes advanced sleep phase.

Authors:  Philip Kurien; Pei-Ken Hsu; Jacy Leon; David Wu; Thomas McMahon; Guangsen Shi; Ying Xu; Anna Lipzen; Len A Pennacchio; Christopher R Jones; Ying-Hui Fu; Louis J Ptáček
Journal:  Proc Natl Acad Sci U S A       Date:  2019-05-28       Impact factor: 11.205

3.  Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function.

Authors:  Danny M Chou; Stephen J Elledge
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-20       Impact factor: 11.205

4.  A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta.

Authors:  Tsuyoshi Hirota; Warren G Lewis; Andrew C Liu; Jae Wook Lee; Peter G Schultz; Steve A Kay
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-22       Impact factor: 11.205

Review 5.  The human intra-S checkpoint response to UVC-induced DNA damage.

Authors:  William K Kaufmann
Journal:  Carcinogenesis       Date:  2009-09-30       Impact factor: 4.944

Review 6.  Circadian oscillator proteins across the kingdoms of life: structural aspects.

Authors:  Reena Saini; Mariusz Jaskolski; Seth J Davis
Journal:  BMC Biol       Date:  2019-02-18       Impact factor: 7.431

7.  Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts.

Authors:  Stephanie L Smith-Roe; Shivani S Patel; Yingchun Zhou; Dennis A Simpson; Shangbang Rao; Joseph G Ibrahim; Marila Cordeiro-Stone; William K Kaufmann
Journal:  Cell Cycle       Date:  2012-01-15       Impact factor: 4.534

8.  The human Tim-Tipin complex interacts directly with DNA polymerase epsilon and stimulates its synthetic activity.

Authors:  Valentina Aria; Mariarita De Felice; Roberta Di Perna; Shuji Uno; Hisao Masai; Juhani E Syväoja; Barbara van Loon; Ulrich Hübscher; Francesca M Pisani
Journal:  J Biol Chem       Date:  2013-03-19       Impact factor: 5.157

9.  Central clock regulates the cervically stimulated prolactin surges by modulation of dopamine and vasoactive intestinal polypeptide release in ovariectomized rats.

Authors:  Maristela O Poletini; Jessica E Kennett; De'nise T McKee; Marc E Freeman
Journal:  Neuroendocrinology       Date:  2009-10-29       Impact factor: 4.914

10.  Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1.

Authors:  Eishi Noguchi; Chiaki Noguchi; Li-Lin Du; Paul Russell
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272
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