Literature DB >> 10902630

Pharmacological implications of lengthened in-utero exposure to nevirapine.

G P Taylor, E G Lyall, D Back, C Ward, G Tudor-Williams.   

Abstract

Given as a single dose to the mother during labour, nevirapine can protect the neonate from HIV-1 infection for up to 7 days. However, after maternal nevirapine therapy during pregnancy, neonatal plasma concentrations of nevirapine decline more rapidly, suggesting in-utero liver enzyme induction.

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Year:  2000        PMID: 10902630     DOI: 10.1016/s0140-6736(00)02383-7

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  6 in total

1.  Implications of gender and pregnancy for antiretroviral drug dosing.

Authors:  Brookie M Best; Edmund V Capparelli
Journal:  Curr Opin HIV AIDS       Date:  2008-05       Impact factor: 4.283

Review 2.  Antiretroviral therapy in pregnancy: a focus on safety.

Authors:  G P Taylor; N Low-Beer
Journal:  Drug Saf       Date:  2001       Impact factor: 5.606

Review 3.  Pharmacokinetics of antiretrovirals in pregnant women.

Authors:  Mark Mirochnick; Edmund Capparelli
Journal:  Clin Pharmacokinet       Date:  2004       Impact factor: 6.447

Review 4.  Protecting the fetus against HIV infection: a systematic review of placental transfer of antiretrovirals.

Authors:  Shelley A McCormack; Brookie M Best
Journal:  Clin Pharmacokinet       Date:  2014-11       Impact factor: 6.447

5.  Uncomplicated outcome after an accidental overdose of nevirapine in a newborn.

Authors:  Jean-François Brasme; Frédéric Mille; Mounir Benhayoun; Françoise Bavoux; Albert Faye; Natacha Teissier; Eric Lachassinne; Stéphane Dauger
Journal:  Eur J Pediatr       Date:  2007-06-29       Impact factor: 3.860

6.  German-Austrian recommendations for HIV1-therapy in pregnancy and in HIV1-exposed newborn, update 2008.

Authors:  Bernd Buchholz; Matthias Beichert; Ulrich Marcus; Thomas Grubert; Andrea Gingelmaier; Annette Haberl; Brigitte Schmied
Journal:  Eur J Med Res       Date:  2009-11-03       Impact factor: 2.175

  6 in total

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