Literature DB >> 10895375

Insufficiency fractures in rheumatic patients: misdiagnosis and underlying characteristics.

O Elkayam1, D Paran, G Flusser, I Wigler, M Yaron, D Caspi.   

Abstract

OBJECTIVE: To report 9 patients with rheumatic diseases referred to our observation due to presumed exacerbation of their rheumatic disease, subsequently diagnosed as stress insufficiency fractures, and to characterize the clinical profile of patients prone to this complication.
METHODS: The medical history of the patients was reviewed with special emphasis on their rheumatic disease, its course, duration and management, their menopausal state, location and characteristics of the fracture, its presentation and the initial presumed diagnosis, the delay in diagnosis, imaging diagnostic tests performed and outcome. Three representative case reports are presented.
RESULTS: All 9 patients were women, 8 of them aged 50 years old or more, 8 with rheumatoid arthritis and 1 with polymyalgia rheumatica. They were all treated with corticosteroids and had reduction in their bone mass density when evaluated. Three of the patients presented with subcapital fracture of the femur, 4 had fractures of metatarsal bones and 2 had fractures of the distal tibia. In only one patient was a stress fracture initially suspected. Diagnosis was delayed by a mean of 31 days.
CONCLUSION: The diagnosis of stress fractures in patients with rheumatic diseases may often be delayed or missed, and thus improperly treated. Increased awareness of this entity is of importance for prompt diagnosis and correct management.

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Mesh:

Year:  2000        PMID: 10895375

Source DB:  PubMed          Journal:  Clin Exp Rheumatol        ISSN: 0392-856X            Impact factor:   4.473


  6 in total

1.  Insufficiency fractures of the knee, ankle, and foot in rheumatoid arthritis: A case series and case-control study.

Authors:  Aysun Yurtsever; Steen Kåre Fagerberg; Claus Rasmussen
Journal:  Eur J Rheumatol       Date:  2020-07-21

2.  [Insufficiency fractures in rheumatology. Case report and overview].

Authors:  R Dreher; F Buttgereit; W Demary; B Görtz; G Hein; P Kern; A Schulz
Journal:  Z Rheumatol       Date:  2006-09       Impact factor: 1.372

Review 3.  [Drug-induced osteopathy in rheumatology].

Authors:  Christoph Fiehn; Jutta Bauhammer
Journal:  Z Rheumatol       Date:  2022-01-10       Impact factor: 1.372

4.  Antiphospholipid antibodies, systemic lupus erythematosus, and non-traumatic metatarsal fractures.

Authors:  S Sangle; D P D'Cruz; M A Khamashta; G R V Hughes
Journal:  Ann Rheum Dis       Date:  2004-10       Impact factor: 19.103

Review 5.  Looking beyond low bone mineral density: multiple insufficiency fractures in a woman with post-menopausal osteoporosis on alendronate therapy.

Authors:  P Lee; H van der Wall; M J Seibel
Journal:  J Endocrinol Invest       Date:  2007 Jul-Aug       Impact factor: 4.256

Review 6.  The Effect of Anti-rheumatic Drugs on the Skeleton.

Authors:  B Hauser; H Raterman; S H Ralston; W F Lems
Journal:  Calcif Tissue Int       Date:  2022-06-30       Impact factor: 4.000

  6 in total

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