Literature DB >> 16944082

[Insufficiency fractures in rheumatology. Case report and overview].

R Dreher1, F Buttgereit, W Demary, B Görtz, G Hein, P Kern, A Schulz.   

Abstract

Stress fractures occur as insufficiency fractures, with a prevalence of 0.8% in patients with rheumatological illness. The main sites of insufficiency fractures are the pelvis and sacrum, parts of the tibia and fibula that are close to the joints, and the calcaneus and hip. Since the painful symptoms overlap with the clinical picture of the painful joint diseases and because of the low sensitivity of conventional diagnostic X-ray, insufficiency fractures are not diagnosed directly or their diagnosis is delayed. The high sensitivity of computer tomography, skeletal scintigraphy and nuclear magnetic resonance imaging should be exploited in the diagnosis of insufficiency fractures. The case report presented describes insufficiency fractures of the distal right tibia and fibula in an elderly female patient with rheumatoid arthritis being treated with long-term glucocorticoids. In addition to advanced age, female gender, immobility and rheumatoid arthritis requiring long-term cortisone, there are further risk factors for insufficiency fractures: fluoride treatment over many years in the past, hypovitaminosis D3, renal failure. The DXA bone density values of the neck of the femur and the lumbar vertebrae do not show any osteoporosis, and the calcium concentration in the serum is low; phosphate is raised and parathormone is normal; osteocalcin, beta crosslaps and alkaline phosphatase are raised. Bone biopsy specimens taken from the iliac crest and the proximal femur and investigated for the purpose of differential diagnosis revealed renal osteopathy with secondary hyperparathyroidism and osteomalacia. In elderly patients with kidney failure, the possibility of renal osteopathy must be considered as the possible cause of reduced bone quality with a raised risk of insufficiency fractures, even when the parathormone levels are normal. In view of the frequency of osteopathies in rheumatological patients, osteology is of enormous significance in rheumatology.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16944082     DOI: 10.1007/s00393-006-0089-5

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  39 in total

1.  Influence of nonenzymatic glycation on biomechanical properties of cortical bone.

Authors:  D Vashishth; G J Gibson; J I Khoury; M B Schaffler; J Kimura; D P Fyhrie
Journal:  Bone       Date:  2001-02       Impact factor: 4.398

2.  Corticosteroid use and risk of hip fracture: a population-based case-control study in Denmark.

Authors:  P Vestergaard; M L Olsen; S Paaske Johnsen; L Rejnmark; H Toft Sørensen; L Mosekilde
Journal:  J Intern Med       Date:  2003-11       Impact factor: 8.989

3.  Correlation of bone mineral density with the histological findings of renal osteodystrophy in patients on hemodialysis.

Authors:  A Gerakis; D Hadjidakis; E Kokkinakis; T Apostolou; S Raptis; A Billis
Journal:  J Nephrol       Date:  2000 Nov-Dec       Impact factor: 3.902

4.  Combined calcium and vitamin D3 supplementation in elderly women: confirmation of reversal of secondary hyperparathyroidism and hip fracture risk: the Decalyos II study.

Authors:  M C Chapuy; R Pamphile; E Paris; C Kempf; M Schlichting; S Arnaud; P Garnero; P J Meunier
Journal:  Osteoporos Int       Date:  2002-03       Impact factor: 4.507

Review 5.  Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications.

Authors:  P Lips
Journal:  Endocr Rev       Date:  2001-08       Impact factor: 19.871

6.  Increased risk of hip fracture among patients with end-stage renal disease.

Authors:  A M Alem; D J Sherrard; D L Gillen; N S Weiss; S A Beresford; S R Heckbert; C Wong; C Stehman-Breen
Journal:  Kidney Int       Date:  2000-07       Impact factor: 10.612

Review 7.  Percutaneous bone biopsy in the diagnosis of renal osteodystrophy.

Authors:  Louisa T Ho; Stuart M Sprague
Journal:  Semin Nephrol       Date:  2002-05       Impact factor: 5.299

8.  Low dose long-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious adverse events.

Authors:  K G Saag; R Koehnke; J R Caldwell; R Brasington; L F Burmeister; B Zimmerman; J A Kohler; D E Furst
Journal:  Am J Med       Date:  1994-02       Impact factor: 4.965

9.  Cortisol downregulates osteoblast alpha 1 (I) procollagen mRNA by transcriptional and posttranscriptional mechanisms.

Authors:  A M Delany; B Y Gabbitas; E Canalis
Journal:  J Cell Biochem       Date:  1995-03       Impact factor: 4.429

10.  Insufficiency fracture. A survey of 60 cases and review of the literature.

Authors:  Martin Soubrier; Jean-Jacques Dubost; Stephane Boisgard; Bernard Sauvezie; Pierre Gaillard; Jean Luc Michel; Jean Michel Ristori
Journal:  Joint Bone Spine       Date:  2003-06       Impact factor: 4.929

View more
  3 in total

1.  [Insufficiency fractures of the feet and lower limbs in rheumatoid arthritis].

Authors:  J Pauser; H-D Carl; B Swoboda; K A Jendrissek
Journal:  Z Rheumatol       Date:  2011-12       Impact factor: 1.372

2.  Insufficiency fractures of the knee, ankle, and foot in rheumatoid arthritis: A case series and case-control study.

Authors:  Aysun Yurtsever; Steen Kåre Fagerberg; Claus Rasmussen
Journal:  Eur J Rheumatol       Date:  2020-07-21

3.  Spontaneous bilateral distal ulna fracture: an unusual complication in a rheumatoid patient.

Authors:  Santosh Venkatachalam; Paul Dixon
Journal:  J Orthop Traumatol       Date:  2011-05-20
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.