Literature DB >> 10893716

The nonenzymatic hydrolysis of oligoribonucleotides. VII. Structural elements affecting hydrolysis.

A Bibillo1, M Figlerowicz, K Ziomek, R Kierzek.   

Abstract

Several elements of oligoribonucleotide structure are important for efficient hydrolysis. We have found that the following factors influence oligoribonucleotide hydrolysis: (i) single-stranded structure of RNA flanking the scissile phosphodiester bond, (ii) the substituent on atom C-5 of the uridine adjacent to the cleaved internucleotide bond, (iii) the position of the scissile UA phosphodiester bond within a hairpin loop, (iv) the concentration of formamide, urea, ethanol and sodium chloride.

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Year:  2000        PMID: 10893716     DOI: 10.1080/15257770008033037

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN: 1525-7770            Impact factor:   1.381


  8 in total

1.  The reactivity of phosphodiester bonds within linear single-stranded oligoribonucleotides is strongly dependent on the base sequence.

Authors:  Ulla Kaukinen; Sari Lyytikäinen; Satu Mikkola; Harri Lönnberg
Journal:  Nucleic Acids Res       Date:  2002-01-15       Impact factor: 16.971

2.  Mechanistic insights for β-cyclodextrin catalyzed phosphodiester hydrolysis.

Authors:  Mahboobeh Rahimian; Sachin D Yeole; Shridhar P Gejji
Journal:  J Mol Model       Date:  2014-03-22       Impact factor: 1.810

3.  Random-sequence genetic oligomer pools display an innate potential for ligation and recombination.

Authors:  Hannes Mutschler; Alexander I Taylor; Benjamin T Porebski; Alice Lightowlers; Gillian Houlihan; Mikhail Abramov; Piet Herdewijn; Philipp Holliger
Journal:  Elife       Date:  2018-11-21       Impact factor: 8.713

4.  Relationship of SARS-CoV to other pathogenic RNA viruses explored by tetranucleotide usage profiling.

Authors:  Yee Leng Yap; Xue Wu Zhang; Antoine Danchin
Journal:  BMC Bioinformatics       Date:  2003-09-20       Impact factor: 3.169

5.  Enhanced RNA cleavage within bulge-loops by an artificial ribonuclease.

Authors:  Irina L Kuznetsova; Marina A Zenkova; Hans J Gross; Valentin V Vlassov
Journal:  Nucleic Acids Res       Date:  2005-02-24       Impact factor: 16.971

6.  Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities.

Authors:  Alexander V Sidorov; Jane A Grasby; David M Williams
Journal:  Nucleic Acids Res       Date:  2004-03-05       Impact factor: 16.971

7.  Thermodynamic analysis of 5' and 3' single- and 3' double-nucleotide overhangs neighboring wobble terminal base pairs.

Authors:  Stacy Miller; Laura E Jones; Karen Giovannitti; Dan Piper; Martin J Serra
Journal:  Nucleic Acids Res       Date:  2008-09-02       Impact factor: 16.971

8.  Prebiotically Plausible RNA Activation Compatible with Ribozyme-Catalyzed Ligation.

Authors:  Emilie Yeonwha Song; Eddy Ivanhoe Jiménez; Huacan Lin; Kristian Le Vay; Ramanarayanan Krishnamurthy; Hannes Mutschler
Journal:  Angew Chem Int Ed Engl       Date:  2020-12-10       Impact factor: 16.823

  8 in total

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