| Literature DB >> 10893716 |
A Bibillo1, M Figlerowicz, K Ziomek, R Kierzek.
Abstract
Several elements of oligoribonucleotide structure are important for efficient hydrolysis. We have found that the following factors influence oligoribonucleotide hydrolysis: (i) single-stranded structure of RNA flanking the scissile phosphodiester bond, (ii) the substituent on atom C-5 of the uridine adjacent to the cleaved internucleotide bond, (iii) the position of the scissile UA phosphodiester bond within a hairpin loop, (iv) the concentration of formamide, urea, ethanol and sodium chloride.Entities:
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Year: 2000 PMID: 10893716 DOI: 10.1080/15257770008033037
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN: 1525-7770 Impact factor: 1.381