Literature DB >> 10893602

Urethral diverticulum in women: diverse presentations resulting in diagnostic delay and mismanagement.

L J Romanzi1, A Groutz, J G Blaivas.   

Abstract

PURPOSE: We describe various clinical presentations of urethral diverticulum, which may mimic other pelvic floor disorders and result in diagnostic delay. Management and outcome results are reported.
MATERIALS AND METHODS: We reviewed retrospectively 46 consecutive cases of urethral diverticulum. Patient characteristics, history, clinical evaluation, management and long-term followup are reported.
RESULTS: Mean patient age plus or minus standard deviation was 36.3 +/- 11.7 years. Most (83%) cases were referred as diagnostic dilemmas with symptoms present for 3 months to 27 years. Mean interval between onset of symptoms to diagnosis was 5.2 years. The most common symptoms were pain (48% of cases), urinary incontinence (35%), dyspareunia (24%) and frequency/urgency (22%). The number of physicians previously consulted ranged from 3 to 20 and prior therapies included oral and/or vaginal medications, anti-incontinence surgery and psychotherapy. The diverticulum was palpable on examination in 24 patients (52%), in only 6 of whom was it possible to "milk" contents per meatus. Of these 24 palpable diverticula 2 contained malignancy, and 2 others contained endometriosis and stones, respectively. Diagnosis was made by voiding cystourethrography in 30 cases (65%), double balloon urethrography in 5 (11%) and transvaginal ultrasound or magnetic resonance imaging in 7 (15%). Diverticula were incidental findings during vaginal surgery in 4 cases (9%). Treatment consisted of diverticulectomy and/or Martius flap, pubovaginal sling and urethral reconstructive procedures when indicated in 35 cases (76%), and 2 other patients underwent radical surgery for diverticular malignancy. Subsequently all but 2 patients with pain were cured. In another patient de novo stress incontinence developed postoperatively. None of the patients who underwent concomitant pubovaginal sling had postoperative incontinence.
CONCLUSIONS: The symptoms of urethral diverticulum may mimic other disorders. This condition should be considered in women with pelvic pain, urinary incontinence and irritative voiding symptoms not responding to therapy. Surgical treatment is usually effective in alleviating associated symptoms.

Entities:  

Mesh:

Year:  2000        PMID: 10893602

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  23 in total

1.  Obstructing urethral calculus in a woman revealed to be the cause of chronic pelvic pain.

Authors:  J S Thomas; J Crew
Journal:  Int Urogynecol J       Date:  2012-03-10       Impact factor: 2.894

Review 2.  Urethral diverticula: evolving diagnostics and improved surgical management.

Authors:  R Dmochowski
Journal:  Curr Urol Rep       Date:  2001-10       Impact factor: 3.092

3.  Utility of clinical parameters, cystourethroscopy, and magnetic resonance imaging in the preoperative diagnosis of urethral diverticula.

Authors:  Sujatha D Pathi; David D Rahn; Joseph L Sailors; Vincent A Graziano; Robert D Sims; Rebecca J Stone; Donald D McIntire; Clifford Y Wai
Journal:  Int Urogynecol J       Date:  2012-06-16       Impact factor: 2.894

4.  Case report: transitional cell carcinoma in situ within a urethral diverticulum.

Authors:  Jane Manning
Journal:  Int Urogynecol J       Date:  2012-06-06       Impact factor: 2.894

5.  TVT can also cause urethral diverticulum.

Authors:  F T Hammad
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2006-07-05

6.  A modified technique for the surgical correction of urethral diverticula using a porcine xenograft.

Authors:  James W S Lee; Stergios K Doumouchtsis; Michelle M Fynes
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2008-07-05

Review 7.  Current evaluation and management of female urethral diverticula.

Authors:  LiAnn N Handel; Gary E Leach
Journal:  Curr Urol Rep       Date:  2008-09       Impact factor: 3.092

Review 8.  MRI of female urethra and periurethral pathologies.

Authors:  Malak Itani; Ania Kielar; Christine O Menias; Manjiri K Dighe; Venkat Surabhi; Srinivasa R Prasad; Ryan O'Malley; Kiran Gangadhar; Neeraj Lalwani
Journal:  Int Urogynecol J       Date:  2015-07-26       Impact factor: 2.894

9.  Three-dimensional volume rendering of pelvic models and paraurethral masses based on MRI cross-sectional images.

Authors:  Stergios K Doumouchtsis; Daron A Nazarian; Nivedita Gauthaman; Constantin M Durnea; Graham Munneke
Journal:  Int Urogynecol J       Date:  2017-03-28       Impact factor: 2.894

10.  Periurethral Gland Calculus Discovered on Workup for Dyspareunia.

Authors:  Ryan P Terlecki; Susan M MacDonald
Journal:  Curr Urol       Date:  2017-03-30
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