Literature DB >> 10891240

New stable reagents for the nucleophilic trifluoromethylation. 1. Trifluoromethylation Of carbonyl compounds with N-formylmorpholine derivatives

.   

Abstract

A new stable equivalent of the trifluoromethyl anion has been synthesized from fluoroform. It reacts with nonenolizable carbonyl compounds such as the Ruppert's reagent.

Entities:  

Year:  2000        PMID： 10891240     DOI： 10.1021/ol005987o

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Copper-catalyzed trifluoromethylation of unactivated olefins.

Authors:  Andrew T Parsons; Stephen L Buchwald
Journal:  Angew Chem Int Ed Engl       Date:  2011-08-25       Impact factor: 15.336

2.  Nucleophilic trifluoromethylation of carbonyl compounds: trifluoroacetaldehyde hydrate as a trifluoromethyl source.

Authors:  G K Surya Prakash; Zhe Zhang; Fang Wang; Socrates Munoz; George A Olah
Journal:  J Org Chem       Date:  2013-02-28       Impact factor: 4.354

3.  Regioselective 1,4-trifluoromethylation of α,β-unsaturated ketones via a S-(trifluoromethyl)diphenylsulfonium salts/copper system.

Authors:  Satoshi Okusu; Yutaka Sugita; Etsuko Tokunaga; Norio Shibata
Journal:  Beilstein J Org Chem       Date:  2013-10-23       Impact factor: 2.883

4.  Fluorine-decoupled carbon spectroscopy for the determination of configuration at fully substituted, trifluoromethyl- and perfluoroalkyl-bearing carbons: comparison with 19F-1H heteronuclear Overhauser effect spectroscopy.

Authors:  Appi Reddy Mandhapati; Takayuki Kato; Takahiko Matsushita; Bashar Ksebati; Andrea Vasella; Erik C Böttger; David Crich
Journal:  J Org Chem       Date:  2015-01-20       Impact factor: 4.354

5.  Synthesis of trifluoromethyl ketones by nucleophilic trifluoromethylation of esters under a fluoroform/KHMDS/triglyme system.

Authors:  Yamato Fujihira; Yumeng Liang; Makoto Ono; Kazuki Hirano; Takumi Kagawa; Norio Shibata
Journal:  Beilstein J Org Chem       Date:  2021-02-12       Impact factor: 2.883

6.  Organocatalyzed Trifluoromethylation of Ketones and Sulfonyl Fluorides by Fluoroform under a Superbase System.

Authors:  Satoshi Okusu; Kazuki Hirano; Etsuko Tokunaga; Norio Shibata
Journal:  ChemistryOpen       Date:  2015-08-06       Impact factor: 2.911

Review 7.  Carbon-carbon bond cleavage for Cu-mediated aromatic trifluoromethylations and pentafluoroethylations.

Authors:  Tsuyuka Sugiishi; Hideki Amii; Kohsuke Aikawa; Koichi Mikami
Journal:  Beilstein J Org Chem       Date:  2015-12-18       Impact factor: 2.883
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.