Literature DB >> 10884398

Schizophrenia: more dopamine, more D2 receptors.

P Seeman1, S Kapur.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10884398      PMCID： PMC33999          DOI： 10.1073/pnas.97.14.7673

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


× No keyword cloud information.
  21 in total

1.  Antipsychotic agents differ in how fast they come off the dopamine D2 receptors. Implications for atypical antipsychotic action.

Authors:  S Kapur; P Seeman
Journal:  J Psychiatry Neurosci       Date:  2000-03       Impact factor: 6.186

2.  Increased baseline occupancy of D2 receptors by dopamine in schizophrenia.

Authors:  A Abi-Dargham; J Rodenhiser; D Printz; Y Zea-Ponce; R Gil; L S Kegeles; R Weiss; T B Cooper; J J Mann; R L Van Heertum; J M Gorman; M Laruelle
Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-05       Impact factor: 11.205

3.  A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy.

Authors:  S Kapur; R Zipursky; C Jones; C S Shammi; G Remington; P Seeman
Journal:  Arch Gen Psychiatry       Date:  2000-06

4.  Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes.

Authors:  D R Burt; I Creese; S H Snyder
Journal:  Mol Pharmacol       Date:  1976-09       Impact factor: 4.436

5.  Antipsychotic drug doses and neuroleptic/dopamine receptors.

Authors:  P Seeman; T Lee; M Chau-Wong; K Wong
Journal:  Nature       Date:  1976-06-24       Impact factor: 49.962

6.  The relationship between dorsolateral prefrontal neuronal N-acetylaspartate and evoked release of striatal dopamine in schizophrenia.

Authors:  A Bertolino; A Breier; J H Callicott; C Adler; V S Mattay; M Shapiro; J A Frank; D Pickar; D R Weinberger
Journal:  Neuropsychopharmacology       Date:  2000-02       Impact factor: 7.853

7.  In vivo [3H]spiperone binding: evidence for accumulation in corpus striatum by agonist-mediated receptor internalization.

Authors:  D C Chugani; R F Ackermann; M E Phelps
Journal:  J Cereb Blood Flow Metab       Date:  1988-06       Impact factor: 6.200

8.  Rapid release of antipsychotic drugs from dopamine D2 receptors: an explanation for low receptor occupancy and early clinical relapse upon withdrawal of clozapine or quetiapine.

Authors:  P Seeman; T Tallerico
Journal:  Am J Psychiatry       Date:  1999-06       Impact factor: 18.112

9.  Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22.

Authors:  L M Brzustowicz; K A Hodgkinson; E W Chow; W G Honer; A S Bassett
Journal:  Science       Date:  2000-04-28       Impact factor: 47.728

10.  Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

Authors:  P Seeman; M Chau-Wong; J Tedesco; K Wong
Journal:  Proc Natl Acad Sci U S A       Date:  1975-11       Impact factor: 11.205
View more
  75 in total

Review 1.  Animal models of schizophrenia: a critical review.

Authors:  E R Marcotte; D M Pearson; L K Srivastava
Journal:  J Psychiatry Neurosci       Date:  2001-11       Impact factor: 6.186

Review 2.  Cognitive effects of nicotine: genetic moderators.

Authors:  Aryeh I Herman; Mehmet Sofuoglu
Journal:  Addict Biol       Date:  2010-04-29       Impact factor: 4.280

Review 3.  Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders.

Authors:  John L R Rubenstein
Journal:  J Child Psychol Psychiatry       Date:  2010-08-24       Impact factor: 8.982

Review 4.  Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains.

Authors:  Joel E Kleinman; Amanda J Law; Barbara K Lipska; Thomas M Hyde; Justin K Ellis; Paul J Harrison; Daniel R Weinberger
Journal:  Biol Psychiatry       Date:  2011-01-15       Impact factor: 13.382

Review 5.  How antipsychotics work-from receptors to reality.

Authors:  Shitij Kapur; Ofer Agid; Romina Mizrahi; Ming Li
Journal:  NeuroRx       Date:  2006-01

6.  Deficiency of Aph1B/C-gamma-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment.

Authors:  T Dejaegere; L Serneels; M K Schäfer; J Van Biervliet; K Horré; C Depboylu; D Alvarez-Fischer; A Herreman; M Willem; C Haass; G U Höglinger; R D'Hooge; B De Strooper
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-14       Impact factor: 11.205

7.  The H3 antagonist ABT-288 is tolerated at significantly higher exposures in subjects with schizophrenia than in healthy volunteers.

Authors:  Ahmed A Othman; George Haig; Hana Florian; Charles Locke; Lev Gertsik; Sandeep Dutta
Journal:  Br J Clin Pharmacol       Date:  2014-06       Impact factor: 4.335

8.  Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization.

Authors:  Yukihiko Iizuka; Yoshitatsu Sei; Daniel R Weinberger; Richard E Straub
Journal:  J Neurosci       Date:  2007-11-07       Impact factor: 6.167

Review 9.  Basal ganglia pathology in schizophrenia: dopamine connections and anomalies.

Authors:  Emma Perez-Costas; Miguel Melendez-Ferro; Rosalinda C Roberts
Journal:  J Neurochem       Date:  2010-01-20       Impact factor: 5.372

Review 10.  Psychiatric disorders in toxoplasma seropositive patients--the CD8 connection.

Authors:  Rajarshi Bhadra; Dustin A Cobb; Louis M Weiss; Imtiaz A Khan
Journal:  Schizophr Bull       Date:  2013-02-20       Impact factor: 9.306
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.