A Müller1, M J Doughty, L Wright. 1. Glasgow Caledonian University, Department of Vision Sciences, Glasgow G4 0BA.
Abstract
AIM: To assess uniformity of the corneal endothelial cell mosaic in children. METHODS: 36 healthy children (5-11 years old, 16 boys, 20 girls) were assessed by specular microscopy. Endothelial cell density (ECD) was calculated from measured cell areas, and the number of sides/cell noted. RESULTS: Average values for ECD and cell areas were 3987 cells/mm(2) (95% CI 3806 to 4168 cells/mm(2)) and 278 (SD 85) mm(2) respectively, with normal distribution (COV 28. 2%, range 17.4 to 39.2%) and with the average percentage of six sided cells being 66.6% (8.8%). Cell area was positively correlated to number of cell sides (p <0.01, r(2)=0.993), but the percentage of six sided cells was negatively correlated to ECD (p <0.01, r=0.493). CONCLUSION: A high ECD occurs in children, but this does not mean there is a high percentage of "hexagons".
AIM: To assess uniformity of the corneal endothelial cell mosaic in children. METHODS: 36 healthy children (5-11 years old, 16 boys, 20 girls) were assessed by specular microscopy. Endothelial cell density (ECD) was calculated from measured cell areas, and the number of sides/cell noted. RESULTS: Average values for ECD and cell areas were 3987 cells/mm(2) (95% CI 3806 to 4168 cells/mm(2)) and 278 (SD 85) mm(2) respectively, with normal distribution (COV 28. 2%, range 17.4 to 39.2%) and with the average percentage of six sided cells being 66.6% (8.8%). Cell area was positively correlated to number of cell sides (p <0.01, r(2)=0.993), but the percentage of six sided cells was negatively correlated to ECD (p <0.01, r=0.493). CONCLUSION: A high ECD occurs in children, but this does not mean there is a high percentage of "hexagons".
Authors: Brian P Brooks; Amy H Thompson; Janine A Clayton; Chi-Chao Chan; Deborah Tamura; Wadih M Zein; Delphine Blain; Casey Hadsall; John Rowan; Kristen E Bowles; Sikandar G Khan; Takahiro Ueda; Jennifer Boyle; Kyu-Seon Oh; John J DiGiovanna; Kenneth H Kraemer Journal: Ophthalmology Date: 2011-09-28 Impact factor: 12.079
Authors: Brian P Brooks; Amy H Thompson; Rachel J Bishop; Janine A Clayton; Chi-Chao Chan; Ekaterini T Tsilou; Wadih M Zein; Deborah Tamura; Sikandar G Khan; Takahiro Ueda; Jennifer Boyle; Kyu-Seon Oh; Kyoko Imoto; Hiroki Inui; Shin-Ichi Moriwaki; Steffen Emmert; Nicholas T Iliff; Porcia Bradford; John J Digiovanna; Kenneth H Kraemer Journal: Ophthalmology Date: 2013-04-16 Impact factor: 12.079