| Literature DB >> 10866369 |
W Wang1, P Préville, N Morin, S Mounir, W Cai, M A Siddiqui.
Abstract
An in vitro assay based on the expression of Fluci reporter gene under the translational control of HCV IRES was used to evaluate and screen compound libraries. A structure-activity relationship study on a phenazine hit was conducted. Our data suggest that an intact phenazine or phenazine-like core with two distal polar substitutions is crucial for potency.Entities:
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Year: 2000 PMID： 10866369 DOI： 10.1016/s0960-894x(00)00217-1
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823