Literature DB >> 10866217

SB-203207 and SB-203208, two novel isoleucyl tRNA synthetase inhibitors from a Streptomyces sp. I. Fermentation, isolation and properties.

A L Stefanska1, R Cassels, S J Ready, S R Warr.   

Abstract

Two novel inhibitors of isoleucyl tRNA synthetase designated SB-203207 and SB-203208 have been detected in the culture of a new Streptomyces species. The fermentation, isolation and some properties of the inhibitors are described.

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Year:  2000        PMID： 10866217     DOI： 10.7164/antibiotics.53.357

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

Review 1.  Progress and challenges in aminoacyl-tRNA synthetase-based therapeutics.

Authors:  Christopher S Francklyn; Patrick Mullen
Journal:  J Biol Chem       Date:  2019-01-22       Impact factor: 5.157

2.  Characterization of two seryl-tRNA synthetases in albomycin-producing Streptomyces sp. strain ATCC 700974.

Authors:  Yu Zeng; Hervé Roy; Preeti B Patil; Michael Ibba; Shawn Chen
Journal:  Antimicrob Agents Chemother       Date:  2009-08-31       Impact factor: 5.191

3.  Dearomative Synthetic Entry into the Altemicidin Alkaloids.

Authors:  Claire S Harmange Magnani; Thomas J Maimone
Journal:  J Am Chem Soc       Date:  2021-05-21       Impact factor: 16.383

4.  Proline-based phosphoramidite reagents for the reductive ligation of S-nitrosothiols.

Authors:  Chung-Min Park; Tyler D Biggs; Ming Xian
Journal:  J Antibiot (Tokyo)       Date:  2016-01-13       Impact factor: 2.649

Review 5.  Biosynthesis of sulfonamide and sulfamate antibiotics in actinomycete.

Authors:  Takayoshi Awakawa; Lena Barra; Ikuro Abe
Journal:  J Ind Microbiol Biotechnol       Date:  2021-06-04       Impact factor: 4.258

Review 6.  Diversification of aminoacyl-tRNA synthetase activities via genomic duplication.

Authors:  Natalie Krahn; Dieter Söll; Oscar Vargas-Rodriguez
Journal:  Front Physiol       Date:  2022-08-19       Impact factor: 4.755

Review 7.  Noncanonical Functions of Enzyme Cofactors as Building Blocks in Natural Product Biosynthesis.

Authors:  Lena Barra; Takayoshi Awakawa; Ikuro Abe
Journal:  JACS Au       Date:  2022-08-17

8.  Aminoacyl sulfonamide assembly in SB-203208 biosynthesis.

Authors:  Zhijuan Hu; Takayoshi Awakawa; Zhongjun Ma; Ikuro Abe
Journal:  Nat Commun       Date:  2019-01-14       Impact factor: 14.919
  8 in total

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