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Literature DB >> 10860206

Human embryonic stem cells and respect for life.

Abstract

The purpose of this essay is to stimulate academic discussion about the ethical justification of using human primordial stem cells for tissue transplantation, cell replacement, and gene therapy. There are intriguing alternatives to using embryos obtained from elective abortions and in vitro fertilisation to reconstitute damaged or dysfunctional human organs. These include the expansion and transplantation of latent adult progenitor cells.

Entities: Disease Species

Keywords: Biomedical and Behavioral Research; Donum Vitae; Genetics and Reproduction; Human Embryo Research Panel; Religious Approach; Vatican

Mesh：

Year: 2000 PMID： 10860206 PMCID： PMC1733225 DOI： 10.1136/jme.26.3.166

Source DB: PubMed Journal: J Med Ethics ISSN： 0306-6800 Impact factor: 2.903

16 in total

1. Where theologians and geneticists meet.

Authors: James M Gustafson
Journal: Dialog Date: 1994

2. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes.

Authors: J D Flax; S Aurora; C Yang; C Simonin; A M Wills; L L Billinghurst; M Jendoubi; R L Sidman; J H Wolfe; S U Kim; E Y Snyder
Journal: Nat Biotechnol Date: 1998-11 Impact factor: 54.908

3. A common neural progenitor for the CNS and PNS.

Authors: T Mujtaba; M Mayer-Proschel; M S Rao
Journal: Dev Biol Date: 1998-08-01 Impact factor: 3.582

Review 4. Regeneration in the central nervous system: pharmacological intervention, xenotransplantation, and stem cell transplantation.

Authors: D G Jones; C M Redpath
Journal: Clin Anat Date: 1998 Impact factor: 2.414

Review 5. The commodification of human reproductive materials.

Authors: D B Resnik
Journal: J Med Ethics Date: 1998-12 Impact factor: 2.903

Review 6. Neural stem and progenitor cells: a strategy for gene therapy and brain repair.

Authors: D W Pincus; R R Goodman; R A Fraser; M Nedergaard; S A Goldman
Journal: Neurosurgery Date: 1998-04 Impact factor: 4.654

7. The regenerative potential of the periodontal ligament.

Authors: J R Meyer
Journal: J Prosthet Dent Date: 1986-02 Impact factor: 3.426

8. In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain.

Authors: C M Morshead; C G Craig; D van der Kooy
Journal: Development Date: 1998-06 Impact factor: 6.868

Human embryonic stem cells and respect for life.

1. Where theologians and geneticists meet.

2. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes.

3. A common neural progenitor for the CNS and PNS.

Review 4. Regeneration in the central nervous system: pharmacological intervention, xenotransplantation, and stem cell transplantation.

Review 5. The commodification of human reproductive materials.

Review 6. Neural stem and progenitor cells: a strategy for gene therapy and brain repair.

7. The regenerative potential of the periodontal ligament.

8. In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain.

9. Embryonic stem cell lines derived from human blastocysts.

10. Derivation of pluripotent stem cells from cultured human primordial germ cells.

1. Stem cells, embryos, and the environment: a context for both science and ethics.

Review 2. What's in a name? Embryos, entities, and ANTities in the stem cell debate.

Review 3. Therapeutic potential of mesenchymal stem cells for oral and systemic diseases.

Review 4. Stem cells as tools in regenerative therapy for retinal degeneration.