Literature DB >> 22835544

Therapeutic potential of mesenchymal stem cells for oral and systemic diseases.

Reuben H Kim1, Shebli Mehrazarin, Mo K Kang.   

Abstract

Mesenchymal stem cells (MSCs) are adult stem cells whose self-renewal, multipotency, and immunosuppressive functions have been investigated for therapeutic applications. MSCs have used for various systemic organ regenerative therapies, allowing rescue of tissue function in damaged or failing organs. This article reviews the regenerative and immunomodulatory functions of MSCs and their applications in dental, orofacial, and systemic tissue regeneration and treatment of inflammatory disorders. It also addresses challenges to MSC-mediated therapeutics arising from tissue and MSC aging and host immune response against allogenic MSC transplantation, and discusses alternative sources of MSCs aimed at overcoming these limitations.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22835544      PMCID: PMC3426923          DOI: 10.1016/j.cden.2012.05.006

Source DB:  PubMed          Journal:  Dent Clin North Am        ISSN: 0011-8532


  147 in total

1.  Multipotent mesenchymal stem cells with immunosuppressive activity can be easily isolated from dental pulp.

Authors:  Laura Pierdomenico; Laura Bonsi; Mario Calvitti; Damiano Rondelli; Mario Arpinati; Gabriella Chirumbolo; Ennio Becchetti; Cosetta Marchionni; Francesco Alviano; Valentina Fossati; Nicola Staffolani; Michele Franchina; Alberto Grossi; Gian Paolo Bagnara
Journal:  Transplantation       Date:  2005-09-27       Impact factor: 4.939

2.  Bone marrow-impregnated collagen matrix for wound healing: experimental evaluation in a microcirculatory model of angiogenesis, and clinical experience.

Authors:  Shigeru Ichioka; Sachio Kouraba; Naomoi Sekiya; Norihiko Ohura; Takashi Nakatsuka
Journal:  Br J Plast Surg       Date:  2005-07-25

3.  Direct pulp capping with mineral trioxide aggregate: an observational study.

Authors:  George Bogen; Jay S Kim; Leif K Bakland
Journal:  J Am Dent Assoc       Date:  2008-03       Impact factor: 3.634

4.  Administering human adipose-derived mesenchymal stem cells to prevent and treat experimental arthritis.

Authors:  Bin Zhou; Jingdong Yuan; Yixuan Zhou; Maher Ghawji; Yun-Ping Deng; Austin J Lee; Albert J Lee; Usha Nair; Andrew H Kang; David D Brand; Tai June Yoo
Journal:  Clin Immunol       Date:  2011-09-02       Impact factor: 3.969

5.  Immunomodulatory properties of mesenchymal stem cells derived from dental pulp and dental follicle are susceptible to activation by toll-like receptor agonists.

Authors:  Sergej Tomic; Jelena Djokic; Sasa Vasilijic; Dragana Vucevic; Vera Todorovic; Gordana Supic; Miodrag Colic
Journal:  Stem Cells Dev       Date:  2011-02-10       Impact factor: 3.272

6.  Age changes in oral epithelia. Progenitor population, synthesis index and tissue turnover.

Authors:  Y Sharav; M Massler
Journal:  Exp Cell Res       Date:  1967-08       Impact factor: 3.905

7.  Tunnel defects in dentin bridges: their formation following direct pulp capping.

Authors:  C F Cox; R K Sübay; E Ostro; S Suzuki; S H Suzuki
Journal:  Oper Dent       Date:  1996 Jan-Feb       Impact factor: 2.440

8.  Investigation of multipotent postnatal stem cells from human periodontal ligament.

Authors:  Byoung-Moo Seo; Masako Miura; Stan Gronthos; Peter Mark Bartold; Sara Batouli; Jaime Brahim; Marian Young; Pamela Gehron Robey; Cun-Yu Wang; Songtao Shi
Journal:  Lancet       Date:  2004 Jul 10-16       Impact factor: 79.321

9.  Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-cell responses against viral or tumor-associated antigens.

Authors:  Fabio Morandi; Lizzia Raffaghello; Giovanna Bianchi; Francesca Meloni; Annalisa Salis; Enrico Millo; Soldano Ferrone; Vincenzo Barnaba; Vito Pistoia
Journal:  Stem Cells       Date:  2008-02-21       Impact factor: 6.277

Review 10.  Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine.

Authors:  G T-J Huang; S Gronthos; S Shi
Journal:  J Dent Res       Date:  2009-09       Impact factor: 6.116

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  5 in total

Review 1.  Odontogenic epithelial stem cells: hidden sources.

Authors:  Sivan Padma Priya; Akon Higuchi; Salem Abu Fanas; Mok Pooi Ling; Vasantha Kumari Neela; P M Sunil; T R Saraswathi; Kadarkarai Murugan; Abdullah A Alarfaj; Murugan A Munusamy; Suresh Kumar
Journal:  Lab Invest       Date:  2015-09-14       Impact factor: 5.662

Review 2.  Stem cell therapy: A novel treatment approach for oral mucosal lesions.

Authors:  G N Suma; Madhu Pruthi Arora; Manisha Lakhanpal
Journal:  J Pharm Bioallied Sci       Date:  2015 Jan-Mar

3.  Development of oral osteomucosal tissue constructs in vitro and localization of fluorescently-labeled bisphosphonates to hard and soft tissue.

Authors:  Susan Bae; Shuting Sun; Tara Aghaloo; Ju-Eun Oh; Charles E McKenna; Mo K Kang; Ki-Hyuk Shin; Sotirios Tetradis; No-Hee Park; Reuben H Kim
Journal:  Int J Mol Med       Date:  2014-06-11       Impact factor: 4.101

4.  Two Transcripts of FBXO5 Promote Migration and Osteogenic Differentiation of Human Periodontal Ligament Mesenchymal Stem Cells.

Authors:  Lin Liu; Kun Liu; Yanzhe Yan; Zhuangzhuang Chu; Yi Tang; Chunbo Tang
Journal:  Biomed Res Int       Date:  2018-04-19       Impact factor: 3.411

5.  Characterization of the osteogenic potential of mesenchymal stem cells from human periodontal ligament based on cell surface markers.

Authors:  Ruth Alvarez; Hye-Lim Lee; Cun-Yu Wang; Christine Hong
Journal:  Int J Oral Sci       Date:  2015-12-18       Impact factor: 6.344

  5 in total

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