Literature DB >> 10858605

Synthesis of benzylideneacetophenones and their inhibition of lipid peroxidation.

I S Arty1, H Timmerman, M Samhoedi, H van der Goot.   

Abstract

A series of benzylideneacetophenone derivatives have been synthesized and found to show potent inhibition of the lipid peroxidation (LPO) in rat liver microsomes. All 19 compounds prepared in this series are LPO inhibitors. The highest activity was found in para hydroxy derivatives with two meta tert-butyl substituents.

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Year:  2000        PMID： 10858605     DOI： 10.1016/s0223-5234(00)00137-9

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  5 in total

1.  (E)-3-(4-Fluoro-phen-yl)-1-[4-(methyl-sulfan-yl)phen-yl]prop-2-en-1-one.

Authors:  N Anuradha; A Thiruvalluvar; M Mahalinga; R J Butcher
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-10-15

Review 2.  Molecular targets and anticancer activity of quinoline-chalcone hybrids: literature review.

Authors:  Mamdouh F A Mohamed; Gamal El-Din A Abuo-Rahma
Journal:  RSC Adv       Date:  2020-08-21       Impact factor: 4.036

3.  ZnO Catalyzed Efficient Synthesis of Some New 2-Substituted-4,6-diarylpyrimidines.

Authors:  K L Ameta; Biresh Kumar; Nitu S Rathore
Journal:  ISRN Org Chem       Date:  2012-10-15

4.  Crystal structure and Hirshfeld surface analysis of (E)-3-(2-chloro-6-fluoro-phen-yl)-1-(3-fluoro-4-meth-oxy-phen-yl)prop-2-en-1-one.

Authors:  Nur Hafiq Hanif Hassan; Amzar Ahlami Abdullah; Suhana Arshad; Nuridayanti Che Khalib; Ibrahim Abdul Razak
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2016-04-22

5.  Synthesis of Novel 2,3-Dihydro-1,5-Benzothiazepines as α-Glucosidase Inhibitors: In Vitro, In Vivo, Kinetic, SAR, Molecular Docking, and QSAR Studies.

Authors:  Rabia Mehmood; Ehsan Ullah Mughal; Eslam B Elkaeed; Rami J Obaid; Yasir Nazir; Hanan A Al-Ghulikah; Nafeesa Naeem; Munirah M Al-Rooqi; Saleh A Ahmed; Syed Wadood Ali Shah; Amina Sadiq
Journal:  ACS Omega       Date:  2022-08-17
  5 in total

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