Literature DB >> 10858262

Cytocidal and apoptotic effects of the ClyA protein from Escherichia coli on primary and cultured monocytes and macrophages.

X H Lai1, I Arencibia, A Johansson, S N Wai, J Oscarsson, S Kalfas, K G Sundqvist, Y Mizunoe, A Sjöstedt, B E Uhlin.   

Abstract

Cytolysin A (ClyA) is a newly discovered cytolytic protein of Escherichia coli K-12 that mediates a hemolytic phenotype. We show here that highly purified ClyA and ClyA-expressing E. coli were cytotoxic and apoptogenic to fresh as well as cultured human and murine monocytes/macrophages.

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Year:  2000        PMID： 10858262      PMCID： PMC101772          DOI： 10.1128/IAI.68.7.4363-4367.2000

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  29 in total

1.  Signal transduction pathways to apoptosis.

Authors:  D J McConkey; S Orrenius
Journal:  Trends Cell Biol       Date:  1994-10       Impact factor: 20.808

2.  Hns mutant unveils the presence of a latent haemolytic activity in Escherichia coli K-12.

Authors:  J M Gomez-Gomez; J Blazquez; F Baquero; J L Martinez
Journal:  Mol Microbiol       Date:  1996-02       Impact factor: 3.501

3.  The Escherichia coli K-12 sheA gene encodes a 34-kDa secreted haemolysin.

Authors:  F J del Castillo; S C Leal; F Moreno; I del Castillo
Journal:  Mol Microbiol       Date:  1997-07       Impact factor: 3.501

4.  Effects of cations and osmotic protectants on cytolytic activity of Actinobacillus actinomycetemcomitans leukotoxin.

Authors:  M Iwase; E T Lally; P Berthold; H M Korchak; N S Taichman
Journal:  Infect Immun       Date:  1990-06       Impact factor: 3.441

5.  Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation.

Authors:  A H Wyllie
Journal:  Nature       Date:  1980-04-10       Impact factor: 49.962

6.  Establishment and characterization of a human histiocytic lymphoma cell line (U-937).

Authors:  C Sundström; K Nilsson
Journal:  Int J Cancer       Date:  1976-05-15       Impact factor: 7.396

7.  An apoptotic response by J774 macrophage cells is common upon infection with diarrheagenic Escherichia coli.

Authors:  X H Lai; J G Xu; S Melgar; B E Uhlin
Journal:  FEMS Microbiol Lett       Date:  1999-03-01       Impact factor: 2.742

8.  A cytolysin encoded by Salmonella is required for survival within macrophages.

Authors:  S J Libby; W Goebel; A Ludwig; N Buchmeier; F Bowe; F C Fang; D G Guiney; J G Songer; F Heffron
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

9.  Killing of Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus by human polymorphonuclear leukocytes in serum and saliva.

Authors:  A Holm; S Kalfas; S E Holm
Journal:  Oral Microbiol Immunol       Date:  1993-06

Review 10.  Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics.

Authors:  J F Kerr; A H Wyllie; A R Currie
Journal:  Br J Cancer       Date:  1972-08       Impact factor: 7.640
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  35 in total

1.  Cytotoxin ClyA from Escherichia coli assembles to a 13-meric pore independent of its redox-state.

Authors:  Nora Eifler; Michael Vetsch; Marco Gregorini; Philippe Ringler; Mohamed Chami; Ansgar Philippsen; Andrea Fritz; Shirley A Müller; Rudi Glockshuber; Andreas Engel; Ulla Grauschopf
Journal:  EMBO J       Date:  2006-05-11       Impact factor: 11.598

2.  Serologic evidence for effective production of cytolysin A in Salmonella enterica serovars typhi and paratyphi A during human infection.

Authors:  Christine von Rhein; Klaus-Peter Hunfeld; Albrecht Ludwig
Journal:  Infect Immun       Date:  2006-08-21       Impact factor: 3.441

3.  The structure of a cytolytic alpha-helical toxin pore reveals its assembly mechanism.

Authors:  Marcus Mueller; Ulla Grauschopf; Timm Maier; Rudi Glockshuber; Nenad Ban
Journal:  Nature       Date:  2009-06-04       Impact factor: 49.962

4.  Characterization of dominantly negative mutant ClyA cytotoxin proteins in Escherichia coli.

Authors:  Sun Nyunt Wai; Marie Westermark; Jan Oscarsson; Jana Jass; Elke Maier; Roland Benz; Bernt Eric Uhlin
Journal:  J Bacteriol       Date:  2003-09       Impact factor: 3.490

5.  A non-classical assembly pathway of Escherichia coli pore-forming toxin cytolysin A.

Authors:  Monifa Fahie; Fabian B Romano; Christina Chisholm; Alejandro P Heuck; Mark Zbinden; Min Chen
Journal:  J Biol Chem       Date:  2013-09-09       Impact factor: 5.157

6.  Francisella tularensis induces cytopathogenicity and apoptosis in murine macrophages via a mechanism that requires intracellular bacterial multiplication.

Authors:  X H Lai; I Golovliov; A Sjöstedt
Journal:  Infect Immun       Date:  2001-07       Impact factor: 3.441

7.  Characterization of anti-Salmonella enterica serotype Typhi antibody responses in bacteremic Bangladeshi patients by an immunoaffinity proteomics-based technology.

Authors:  Richelle C Charles; Alaullah Sheikh; Bryan Krastins; Jason B Harris; M Saruar Bhuiyan; Regina C LaRocque; Tanya Logvinenko; David A Sarracino; Indira T Kudva; Jana Eisenstein; Michael J Podolsky; Anuj Kalsy; W Abdullah Brooks; Albrecht Ludwig; Manohar John; Stephen B Calderwood; Firdausi Qadri; Edward T Ryan
Journal:  Clin Vaccine Immunol       Date:  2010-06-23

8.  Characterization of a pore-forming cytotoxin expressed by Salmonella enterica serovars typhi and paratyphi A.

Authors:  Jan Oscarsson; Marie Westermark; Sven Löfdahl; Björn Olsen; Helena Palmgren; Yoshimitsu Mizunoe; Sun Nyunt Wai; Bernt Eric Uhlin
Journal:  Infect Immun       Date:  2002-10       Impact factor: 3.441

9.  Inhibition of tumor growth and metastasis by a combination of Escherichia coli-mediated cytolytic therapy and radiotherapy.

Authors:  Sheng-Nan Jiang; Thuy X Phan; Taek-Keun Nam; Vu H Nguyen; Hyung-Seok Kim; Hee-Seung Bom; Hyon E Choy; Yeongjin Hong; Jung-Joon Min
Journal:  Mol Ther       Date:  2010-01-05       Impact factor: 11.454

10.  Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium.

Authors:  Richelle C Charles; Jason B Harris; Michael R Chase; Lauren M Lebrun; Alaullah Sheikh; Regina C LaRocque; Tanya Logvinenko; Sean M Rollins; Abdullah Tarique; Elizabeth L Hohmann; Ian Rosenberg; Bryan Krastins; David A Sarracino; Firdausi Qadri; Stephen B Calderwood; Edward T Ryan
Journal:  PLoS One       Date:  2009-09-10       Impact factor: 3.240
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