UNLABELLED: We measured Protein S-100 serum levels in 66 healthy newborns during the first week of life and in 7 newborns with perinatal acidosis. Normal values (n = 66) constantly ranged between 0.66 and 3.33 microg/l (2.5 and 97.5 percentiles) during the evaluation period. CONCLUSIONS: Newborns with signs of hypoxic-ischaemic encephalopathy (HIE) after perinatal acidosis showed elevated Protein S-100 serum levels, whereas newborns without these signs had normal concentrations. S-100 might thus be a marker of central nervous system damage in newborns. Key words: Asphyxia, brain damage, neonate
UNLABELLED: We measured Protein S-100 serum levels in 66 healthy newborns during the first week of life and in 7 newborns with perinatal acidosis. Normal values (n = 66) constantly ranged between 0.66 and 3.33 microg/l (2.5 and 97.5 percentiles) during the evaluation period. CONCLUSIONS: Newborns with signs of hypoxic-ischaemic encephalopathy (HIE) after perinatal acidosis showed elevated Protein S-100 serum levels, whereas newborns without these signs had normal concentrations. S-100 might thus be a marker of central nervous system damage in newborns. Key words: Asphyxia, brain damage, neonate
Authors: J W Wirds; A E J Duyn; S D Geraerts; E Preijer; J A A M Van Diemen-Steenvoorde; J H Schagen Van Leeuwen; F J L M Haas; W B M Gerritsen; A De Boer; J A Leusink Journal: Arch Dis Child Fetal Neonatal Ed Date: 2003-01 Impact factor: 5.747
Authors: An N Massaro; Taeun Chang; Nadja Kadom; Tammy Tsuchida; Joseph Scafidi; Penny Glass; Robert McCarter; Stephen Baumgart; Gilbert Vezina; Karin B Nelson Journal: J Pediatr Date: 2012-04-10 Impact factor: 4.406