| Literature DB >> 10851379 |
H Openshaw1, O Stuve, J P Antel, R Nash, B T Lund, L P Weiner, A Kashyap, P McSweeney, S Forman.
Abstract
Four of 10 patients who were enrolled on protocols of high-dose immunosuppression with peripheral blood stem cell rescue for MS experienced neurologic worsening while receiving recombinant human granulocyte colony-stimulating factor. There was improvement when methylprednisolone was given to three of the patients, but one patient died of respiratory failure. The mechanism of the neurologic worsening is uncertain.Entities:
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Year: 2000 PMID: 10851379 DOI: 10.1212/wnl.54.11.2147
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910