Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Temperature-sensitive suppressor mutations of the Escherichia coli DNA gyrase B protein.

Literature DB >> 10850814

Temperature-sensitive suppressor mutations of the Escherichia coli DNA gyrase B protein.

S J Blance¹, N L Williams, Z A Preston, J Bishara, M S Smyth, A Maxwell.

Abstract

Escherichia coli strain LE316 contains a mutation in gyrB that results in the substitution of Val164 to Gly and confers both chlorobiocin resistance and temperature sensitivity. Selection for suppressors of the ts phenotype yielded second-site mutations in GyrB at His38 and Thr157. The properties of proteins bearing these mutations have been characterized, and a mechanism of suppression is proposed based upon structural considerations.

Entities: Chemical Gene Mutation Species

Mesh：

Substances：

Year: 2000 PMID： 10850814 PMCID： PMC2144630 DOI： 10.1110/ps.9.5.1035

Source DB: PubMed Journal: Protein Sci ISSN： 0961-8368 Impact factor: 6.725

15 in total

1. Overexpression and purification of bacterial DNA gyrase.

Authors: A Maxwell; A J Howells
Journal: Methods Mol Biol Date: 1999

2. gyrB mutations which confer coumarin resistance also affect DNA supercoiling and ATP hydrolysis by Escherichia coli DNA gyrase.

Authors: A Contreras; A Maxwell
Journal: Mol Microbiol Date: 1992-06 Impact factor: 3.501

3. Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

Authors: D B Wigley; G J Davies; E J Dodson; A Maxwell; G Dodson
Journal: Nature Date: 1991-06-20 Impact factor: 49.962

4. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons.

Authors: A Nicholls; K A Sharp; B Honig
Journal: Proteins Date: 1991

5. Cloning of the DNA gyrase genes under tac promoter control: overproduction of the gyrase A and B proteins.

Authors: P Hallett; A J Grimshaw; D B Wigley; A Maxwell
Journal: Gene Date: 1990-09-01 Impact factor: 3.688

6. Tryptic fragments of the Escherichia coli DNA gyrase A protein.

Authors: R J Reece; A Maxwell
Journal: J Biol Chem Date: 1989-11-25 Impact factor: 5.157

7. Probing the binding of coumarins and cyclothialidines to DNA gyrase.

Authors: S C Kampranis; N A Gormley; R Tranter; G Orphanides; A Maxwell
Journal: Biochemistry Date: 1999-02-16 Impact factor: 3.162

8. An unusual mechanism for resistance to the antibiotic coumermycin A1.

Authors: I del Castillo; J L Vizán; M C Rodríguez-Sáinz; F Moreno
Journal: Proc Natl Acad Sci U S A Date: 1991-10-01 Impact factor: 11.205

Review 9. DNA gyrase: structure and function.

Authors: R J Reece; A Maxwell
Journal: Crit Rev Biochem Mol Biol Date: 1991 Impact factor: 8.250

10. Identifying the catalytic residue of the ATPase reaction of DNA gyrase.

Authors: A P Jackson; A Maxwell
Journal: Proc Natl Acad Sci U S A Date: 1993-12-01 Impact factor: 11.205

8 in total

Review 1. The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts.

Authors: R Craig MacLean; Alex R Hall; Gabriel G Perron; Angus Buckling
Journal: Nat Rev Genet Date: 2010-06 Impact factor: 53.242

2. Quantitative Description of a Protein Fitness Landscape Based on Molecular Features.

Authors: María-Rocío Meini; Pablo E Tomatis; Daniel M Weinreich; Alejandro J Vila
Journal: Mol Biol Evol Date: 2015-03-12 Impact factor: 16.240

3. Rescue of deleterious mutations by the compensatory Y30F mutation in ketosteroid isomerase.

Authors: Hyung Jin Cha; Do Soo Jang; Yeon-Gil Kim; Bee Hak Hong; Jae-Sung Woo; Kyong-Tai Kim; Kwan Yong Choi
Journal: Mol Cells Date: 2013-06-03 Impact factor: 5.034

4. Multiple global suppressors of protein stability defects facilitate the evolution of extended-spectrum TEM β-lactamases.

Authors: Nicholas G Brown; Jeanine M Pennington; Wanzhi Huang; Tulin Ayvaz; Timothy Palzkill
Journal: J Mol Biol Date: 2010-10-16 Impact factor: 5.469