Literature DB >> 10849067

Optimal marker density for interval mapping in a backcross population.

H P Piepho1.   

Abstract

An important question in QTL mapping is the optimal choice of marker density. Using analytical results, it is shown for the case of interval mapping in a backcross population, that the power of QTL detection and the standard errors of genetic effect estimates are little affected by an increase of marker density beyond 10 cM. This finding confirms published simulation results by other authors.

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Year:  2000        PMID： 10849067     DOI： 10.1046/j.1365-2540.2000.00678.x

Source DB:  PubMed          Journal:  Heredity (Edinb)        ISSN： 0018-067X            Impact factor:   3.821


  18 in total

1.  Marker pair selection for mapping quantitative trait loci.

Authors:  H P Piepho; H G Gauch
Journal:  Genetics       Date:  2001-01       Impact factor: 4.562

2.  The use of MapPop1.0 for choosing a QTL mapping sample from an advanced backcross population.

Authors:  C Birolleau-Touchard; E Hanocq; A Bouchez; C Bauland; I Dourlen; J-P Seret; D Rabier; S Hervet; J-F Allienne; Ph Lucas; O Jaminon; R Etienne; G Baudhuin; C Giauffret
Journal:  Theor Appl Genet       Date:  2007-02-14       Impact factor: 5.699

3.  Comparison of biometrical approaches for QTL detection in multiple segregating families.

Authors:  Wenxin Liu; Jochen C Reif; Nicolas Ranc; Giovanni Della Porta; Tobias Würschum
Journal:  Theor Appl Genet       Date:  2012-05-23       Impact factor: 5.699

4.  High-density genotyping: an overkill for QTL mapping? Lessons learned from a case study in maize and simulations.

Authors:  Michael Stange; H Friedrich Utz; Tobias A Schrag; Albrecht E Melchinger; Tobias Würschum
Journal:  Theor Appl Genet       Date:  2013-07-17       Impact factor: 5.699

5.  Gene mapping in the wild with SNPs: guidelines and future directions.

Authors:  Jon Slate; Jake Gratten; Dario Beraldi; Jessica Stapley; Matt Hale; Josephine M Pemberton
Journal:  Genetica       Date:  2008-09-09       Impact factor: 1.082

6.  Discovery and application of insertion-deletion (INDEL) polymorphisms for QTL mapping of early life-history traits in Atlantic salmon.

Authors:  Anti Vasemägi; Riho Gross; Daniel Palm; Tiit Paaver; Craig R Primmer
Journal:  BMC Genomics       Date:  2010-03-08       Impact factor: 3.969

7.  Identification of genetic modifiers of behavioral phenotypes in serotonin transporter knockout rats.

Authors:  Judith Homberg; Isaäc J Nijman; Sylvia Kuijpers; Edwin Cuppen
Journal:  BMC Genet       Date:  2010-05-07       Impact factor: 2.797

8.  Genome-wide mapping and prediction suggests presence of local epistasis in a vast elite winter wheat populations adapted to Central Europe.

Authors:  Sang He; Jochen C Reif; Viktor Korzun; Reiner Bothe; Erhard Ebmeyer; Yong Jiang
Journal:  Theor Appl Genet       Date:  2016-12-19       Impact factor: 5.699

9.  Marker density and read depth for genotyping populations using genotyping-by-sequencing.

Authors:  Timothy M Beissinger; Candice N Hirsch; Rajandeep S Sekhon; Jillian M Foerster; James M Johnson; German Muttoni; Brieanne Vaillancourt; C Robin Buell; Shawn M Kaeppler; Natalia de Leon
Journal:  Genetics       Date:  2013-02-14       Impact factor: 4.562

10.  Genetic architecture of complex agronomic traits examined in two testcross populations of rye (Secale cereale L.).

Authors:  Thomas Miedaner; Marlen Hübner; Viktor Korzun; Brigitta Schmiedchen; Eva Bauer; Grit Haseneyer; Peer Wilde; Jochen C Reif
Journal:  BMC Genomics       Date:  2012-12-17       Impact factor: 3.969
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