Literature DB >> 10845396

Antiangiogenic therapy in brain tumor models.

H J Bernsen1, A J van der Kogel.   

Abstract

The prognosis of patients with malignant brain tumors remains poor despite new developments in neurosurgery, chemotherapy and radiotherapy. Malignant gliomas are highly vascularized, and there is ample evidence that their growth is angiogenesis-dependent. Therefore, new therapeutic approaches often include the inhibition of angiogenesis. In this review, experimental studies of antiangiogenic agents in brain tumor models are summarized. The results of these experiments as well as potential pitfalls in extrapolation to the clinic are discussed.

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Year:  1999        PMID： 10845396     DOI： 10.1023/a:1006395802727

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  54 in total

Review 1.  Management of malignant glioma: role of surgery in relation to multimodality therapy.

Authors:  P Black
Journal:  J Neurovirol       Date:  1998-04       Impact factor: 2.643

2.  Brain tumor therapy: new horizons, new hope.

Authors:  L M DeAngelis
Journal:  Neurology       Date:  1998-05       Impact factor: 9.910

Review 3.  Gene therapy strategies for tumor antiangiogenesis.

Authors:  H L Kong; R G Crystal
Journal:  J Natl Cancer Inst       Date:  1998-02-18       Impact factor: 13.506

4.  A quantitative analysis of vascularization and perfusion of human glioma xenografts at different implantation sites.

Authors:  H J Bernsen; P F Rijken; N E Hagemeier; A J van der Kogel
Journal:  Microvasc Res       Date:  1999-05       Impact factor: 3.514

Review 5.  In vitro and in vivo models for the study of brain tumour invasion.

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Journal:  Anticancer Res       Date:  1997 Nov-Dec       Impact factor: 2.480

6.  Effect of ibuprofen on tumor growth in the C6 spheroid implantation glioma model.

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Journal:  J Neurosurg       Date:  1988-06       Impact factor: 5.115

7.  Suramin inhibits glioma cell proliferation in vitro and in the brain.

Authors:  S Takano; S Gately; H Engelhard; A M Tsanaclis; S Brem
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

8.  Modulation of angiogenesis by human glioma xenograft models that differentially express vascular endothelial growth factor.

Authors:  J Ma; Z L Fei; A Klein-Szanto; J M Gallo
Journal:  Clin Exp Metastasis       Date:  1998-08       Impact factor: 5.150

9.  Antitumor effect of TNP-470 on glial tumors transplanted in rats.

Authors:  N Isobe; T Uozumi; K Kurisu; K Kawamoto
Journal:  Anticancer Res       Date:  1996 Jan-Feb       Impact factor: 2.480

10.  Endothelial differentiation in intracerebral and subcutaneous experimental gliomas.

Authors:  O Arosarena; C Guerin; H Brem; J Laterra
Journal:  Brain Res       Date:  1994-03-21       Impact factor: 3.252
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  9 in total

Review 1.  Predictive oncology: a review of multidisciplinary, multiscale in silico modeling linking phenotype, morphology and growth.

Authors:  Sandeep Sanga; Hermann B Frieboes; Xiaoming Zheng; Robert Gatenby; Elaine L Bearer; Vittorio Cristini
Journal:  Neuroimage       Date:  2007-06-07       Impact factor: 6.556

Review 2.  Brain perfusion CT: principles, technique and clinical applications.

Authors:  A Cianfoni; C Colosimo; M Basile; M Wintermark; L Bonomo
Journal:  Radiol Med       Date:  2007-12-13       Impact factor: 3.469

3.  Growth properties of SF188/V+ human glioma in rats in vivo observed by magnetic resonance imaging.

Authors:  Rachel Grossman; Betty Tyler; Henry Brem; Charles G Eberhart; Silun Wang; De-Xue Fu; Zhibo Wen; Jinyuan Zhou
Journal:  J Neurooncol       Date:  2012-09-27       Impact factor: 4.130

4.  Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme.

Authors:  Jochen Tuettenberg; Rainer Grobholz; Tobias Korn; Frederik Wenz; Ralf Erber; Peter Vajkoczy
Journal:  J Cancer Res Clin Oncol       Date:  2004-09-28       Impact factor: 4.553

5.  Nonlinear modelling of cancer: bridging the gap between cells and tumours.

Authors:  J S Lowengrub; H B Frieboes; F Jin; Y-L Chuang; X Li; P Macklin; S M Wise; V Cristini
Journal:  Nonlinearity       Date:  2010

6.  Computer simulation of glioma growth and morphology.

Authors:  Hermann B Frieboes; John S Lowengrub; S Wise; X Zheng; Paul Macklin; Elaine L Bearer; Vittorio Cristini
Journal:  Neuroimage       Date:  2007-03-23       Impact factor: 6.556

7.  Halofuginone inhibits angiogenesis and growth in implanted metastatic rat brain tumor model--an MRI study.

Authors:  Rinat Abramovitch; Anna Itzik; Hila Harel; Arnon Nagler; Israel Vlodavsky; Tali Siegal
Journal:  Neoplasia       Date:  2004 Sep-Oct       Impact factor: 5.715

8.  Targeted brain tumor treatment-current perspectives.

Authors:  N S Ningaraj; B P Salimath; U T Sankpal; R Perera; T Vats
Journal:  Drug Target Insights       Date:  2007-08-17

Review 9.  Non-cytotoxic therapies for malignant gliomas.

Authors:  Umberto Basso; Mario Ermani; Francesca Vastola; Alba A Brandes
Journal:  J Neurooncol       Date:  2002-05       Impact factor: 4.506
  9 in total

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