Literature DB >> 10843209

Structure-activity relationships of halichondrin B analogues: modifications at C.30-C.38.

Y Wang1, G J Habgood, W J Christ, Y Kishi, B A Littlefield, M J Yu.   

Abstract

Structurally simplified analogues of halichondrin B were prepared by total synthesis and found to retain potent cell growth inhibitory activity in vitro.

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Year:  2000        PMID： 10843209     DOI： 10.1016/s0960-894x(00)00150-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

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4.  A unified strategy for the total syntheses of eribulin and a macrolactam analogue of halichondrin B.

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Review 8.  Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis.

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  8 in total

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