Literature DB >> 1083894

An estimation of the frequency of precursor cells which generate cytotoxic lymphocytes.

M A Skinner, J Marbrook.   

Abstract

The cell-mediated immune response has been generated in vitro with a polyacrylamide culture system which allows the segregation of foci (clones?) of cytotoxic lymphocytes. Using the method of limiting dilutions, the frequency of precursor cells in CBA spleen cells able to generate a cytotoxic response against DBA mastocytoma is estimated at 1 per 1,700 cells.

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Year:  1976        PMID： 1083894      PMCID： PMC2190219          DOI： 10.1084/jem.143.6.1562

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  13 in total

1.  A simplified 51Cr-release assay for killer cells.

Authors:  R M Thorn; J C Palmer; L A Manson
Journal:  J Immunol Methods       Date:  1974-03       Impact factor: 2.303

2.  The in vitro response to sheep erythrocytes by mouse spleen cells: segregation of distinct events leading to antibody formation.

Authors:  J Marbrook; J S Haskill
Journal:  Cell Immunol       Date:  1974-07       Impact factor: 4.868

3.  Enumeration of activated thymus-derived lymphocytes by the virus plaque assay.

Authors:  S Kano; B R Bloom; M L Howe
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

4.  Cell-mediated immune response in vitro. I. A new in vitro system for the generation of cell-mediated cytotoxic activity.

Authors:  H Wagner; M Feldmann
Journal:  Cell Immunol       Date:  1972-03       Impact factor: 4.868

5.  Cellular immunity in vitro. Clonal proliferation of antigen-stimulated lymphocytes.

Authors:  W H Marshall; F T Valentine; H S Lawrence
Journal:  J Exp Med       Date:  1969-08-01       Impact factor: 14.307

6.  Studies of allograft immunity in mice. I. Induction, development and in vitro assay of cellular immunity.

Authors:  K T Brunner; J Mauel; H Rudolf; B Chapuis
Journal:  Immunology       Date:  1970-04       Impact factor: 7.397

7.  Early cellular events in a systemic graft-vs.-host reaction. I. The migration of responding and nonresponding donor lymphocytes.

Authors:  R C Atkins; W L Ford
Journal:  J Exp Med       Date:  1975-03-01       Impact factor: 14.307

8.  Early cellular events in a systemic graft-vs.-host reaction. II. Autoradiographic estimates of the frequency of donor lymphocytes which respond to each Ag-B-determined antigenic complex.

Authors:  W L Ford; S J Simmonds; R C Atkins
Journal:  J Exp Med       Date:  1975-03-01       Impact factor: 14.307

9.  Cell-mediated lympholysis. Importance of serologically defined H-2 regions.

Authors:  B J Alter; D J Schendel; M L Bach; F H Bach; J Klein; J H Stimpfling
Journal:  J Exp Med       Date:  1973-05-01       Impact factor: 14.307

10.  A plaque assay for enumerating antigen-sensitive cells in delayed-type hypersensitivity.

Authors:  B R Bloom; L Jimenez; P I Marcus
Journal:  J Exp Med       Date:  1970-07-01       Impact factor: 14.307
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  31 in total

1.  The receptor specificity of alloreactive T cells. Distinction between stimulator K, I, and D region products and degeneracy of third-party H-2 recognition by low-affinity T cells.

Authors:  Z A Nagy; B E Elliott
Journal:  J Exp Med       Date:  1979-12-01       Impact factor: 14.307

2.  Killer cells reactive to altered-self antigens can also be alloreactive.

Authors:  M J Bevan
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

3.  Anti H-2Dd alloreactivity mediated by herpes-simplex-virus specific cytotoxic H-2k T lymphocytes is associated with H-2Dk.

Authors:  K Pfizenmaier; H Jung; R Kurrle; M Röllinghoff; H Wagner
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

4.  Spontaneous development of functionally active long-term monocytelike cell lines from channel catfish.

Authors:  A N Vallejo; C F Ellsaesser; N W Miller; L W Clem
Journal:  In Vitro Cell Dev Biol       Date:  1991-04

Review 5.  The structural basis of alloreactivity.

Authors:  R Lechler; G Lombardi
Journal:  Immunol Res       Date:  1990       Impact factor: 2.829

Review 6.  Immunological considerations for embryonic and induced pluripotent stem cell banking.

Authors:  Craig J Taylor; Eleanor M Bolton; J Andrew Bradley
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-08-12       Impact factor: 6.237

7.  Distribution of alloreactivity among antigen-specific, class II-restricted T-cell clones and hybridomas.

Authors:  E Bux; K Matsunaga; T Nagatani; P Walden; Z A Nagy; J Klein
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

8.  Frequency of cytotoxic T lymphocyte precursors to herpes simplex virus type 1 as determined by limiting dilution analysis.

Authors:  B T Rouse; H S Larsen; H Wagner
Journal:  Infect Immun       Date:  1983-02       Impact factor: 3.441

9.  Role of H-2 antigens in the host response to methylcholanthrene-induced tumors.

Authors:  L Ahrlund-Richter; E Klein; F Merino
Journal:  Immunogenetics       Date:  1982-01       Impact factor: 2.846

10.  Cytotoxic T-memory cells in virus infection and the specificity of helper T cells.

Authors:  B A Askonas; A Mullbacher; R B Ashman
Journal:  Immunology       Date:  1982-01       Impact factor: 7.397
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