| Literature DB >> 1083696 |
Abstract
Cats with one normal eye and one eye with experimental glaucoma were trained to tolerate tonometry while conscious. They were then given the general anesthetic agents pentobarbital, ketamine, and CI-744 in the lowest and twice the lowest dosages which permitted tonometry in untrained cats. Pentobarbital lowered intraocular pressure (IOP) by 20-50%. Ketamine raised IOP by about 10%. CI-744 had essentially no effect on IOP. The two conpoments of CI-744, tiletamine (CI-634) and zolazepam (CI-716) were given individually in the doses in which they had been given as part of CI-744. Tiletamine had no effect on IOP, while zolazepam lowered IOP by about 10%.Entities:
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Year: 1976 PMID： 1083696 DOI： 10.1007/bf02385214
Source DB: PubMed Journal: Albrecht Von Graefes Arch Klin Exp Ophthalmol ISSN： 0065-6100