Literature DB >> 10835540

Human anti-mouse antibodies.

G G Klee1.   

Abstract

Human anti-mouse antibodies (HAMA) are human immunoglobulins with specificity for mouse immunoglobulins. This topic currently is of interest because of the increased use of monoclonal mouse antibodies as diagnostic reagents both for in vitro laboratory measurements and for in vivo imaging studies. Monoclonal mouse antibodies also are being used therapeutically. This short article reviews the production of HAMA in patients receiving monoclonal antibodies and illustrates the potential ways that HAMA can interfere with immunoassay measurements. Methods for measuring and neutralizing HAMA also are discussed.

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Year:  2000        PMID： 10835540     DOI： 10.5858/2000-124-0921-HAMA

Source DB:  PubMed          Journal:  Arch Pathol Lab Med        ISSN： 0003-9985            Impact factor:   5.534


  32 in total

1.  Trimester-specific reference intervals for thyroxine and triiodothyronine in pregnancy in iodine-sufficient women using isotope dilution tandem mass spectrometry and immunoassays.

Authors:  O P Soldin; L Hilakivi-Clarke; E Weiderpass; S J Soldin
Journal:  Clin Chim Acta       Date:  2004-11       Impact factor: 3.786

Review 2.  Molecular engineering of antibodies for therapeutic and diagnostic purposes.

Authors:  Frédéric Ducancel; Bruno H Muller
Journal:  MAbs       Date:  2012-07-01       Impact factor: 5.857

Review 3.  From the bench to clinical practice: understanding the challenges and uncertainties in immunogenicity testing for biopharmaceuticals.

Authors:  G R Gunn; D C F Sealey; F Jamali; B Meibohm; S Ghosh; G Shankar
Journal:  Clin Exp Immunol       Date:  2016-01-19       Impact factor: 4.330

Review 4.  Thyroid function testing in pregnancy and thyroid disease: trimester-specific reference intervals.

Authors:  Offie P Soldin
Journal:  Ther Drug Monit       Date:  2006-02       Impact factor: 3.681

5.  Gestation-specific thyroxine and thyroid stimulating hormone levels in the United States and worldwide.

Authors:  Offie P Soldin; Danielle Soldin; Marisol Sastoque
Journal:  Ther Drug Monit       Date:  2007-10       Impact factor: 3.681

6.  Production of a germline-humanized cetuximab scFv and evaluation of its activity in recognizing EGFR- overexpressing cancer cells.

Authors:  Arsham Banisadr; Yaghoub Safdari; Anvarsadat Kianmehr; Mahdieh Pourafshar
Journal:  Hum Vaccin Immunother       Date:  2017-12-21       Impact factor: 3.452

7.  The measurement of free thyroxine by isotope dilution tandem mass spectrometry.

Authors:  Steven J Soldin; Nadia Soukhova; Natasa Janicic; Jacqueline Jonklaas; Offie P Soldin
Journal:  Clin Chim Acta       Date:  2005-04-12       Impact factor: 3.786

8.  Agreement of immunoassay and tandem mass spectrometry in the analysis of cortisol and free t4: interpretation and implications for clinicians.

Authors:  Rochelle E Tractenberg; Jacqueline Jonklaas; Steven J Soldin
Journal:  Int J Anal Chem       Date:  2010-07-12       Impact factor: 1.885

9.  Differences between measurements of T4 and T3 in pregnant and nonpregnant women using isotope dilution tandem mass spectrometry and immunoassays: are there clinical implications?

Authors:  Offie P Soldin; Rochelle E Tractenberg; Steven J Soldin
Journal:  Clin Chim Acta       Date:  2004-09       Impact factor: 3.786

10.  Isotope dilution tandem mass spectrometric method for T4/T3.

Authors:  Nadia Soukhova; Offie P Soldin; Steven J Soldin
Journal:  Clin Chim Acta       Date:  2004-05       Impact factor: 3.786
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