Literature DB >> 10831220

Metal complexes of lactoferrin and their effect on the intracellular multiplication of Legionella pneumophila.

P Goldoni1, L Sinibaldi, P Valenti, N Orsi.   

Abstract

The action of bovine lactoferrin saturated with iron, zinc and manganese on the intracellular multiplication of Legionella pneumophila in HeLa cells has been tested. The results obtained showed that lactoferrin did not influence the invasive efficiency of Legionella. The intracellular multiplication of the bacterium was inhibited by apo-lactoferrin and by lactoferrin saturated with manganese and zinc, whereas lactoferrin saturated with iron enhanced the intracellular growth. Experiments in parallel were performed with iron, manganese and zinc citrate to test the effect due to the metal ions alone. Even in this condition the addition of an iron chelate enhanced the multiplication of Legionella while the manganese chelate produced a certain inhibition.

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Year:  2000        PMID： 10831220     DOI： 10.1023/a:1009221616623

Source DB:  PubMed          Journal:  Biometals        ISSN： 0966-0844            Impact factor:   2.949


  7 in total

1.  The cytochrome c maturation locus of Legionella pneumophila promotes iron assimilation and intracellular infection and contains a strain-specific insertion sequence element.

Authors:  V K Viswanathan; Sherry Kurtz; Lisa L Pedersen; Yousef Abu-Kwaik; Kevin Krcmarik; Sejal Mody; Nicholas P Cianciotto
Journal:  Infect Immun       Date:  2002-04       Impact factor: 3.441

2.  Contribution of the Shigella flexneri Sit, Iuc, and Feo iron acquisition systems to iron acquisition in vitro and in cultured cells.

Authors:  L J Runyen-Janecky; S A Reeves; E G Gonzales; S M Payne
Journal:  Infect Immun       Date:  2003-04       Impact factor: 3.441

Review 3.  Occurrence and Control of Legionella in Recycled Water Systems.

Authors:  Patrick K Jjemba; William Johnson; Zia Bukhari; Mark W LeChevallier
Journal:  Pathogens       Date:  2015-07-01

Review 4.  Lactoferrin a multiple bioactive protein: an overview.

Authors:  Isui Abril García-Montoya; Tania Siqueiros Cendón; Sigifredo Arévalo-Gallegos; Quintín Rascón-Cruz
Journal:  Biochim Biophys Acta       Date:  2011-06-25

Review 5.  The Relationship Between Salivary Redox, Diet, and Food Flavor Perception.

Authors:  Mathieu Schwartz; Fabrice Neiers; Gilles Feron; Francis Canon
Journal:  Front Nutr       Date:  2021-01-28

6.  Legionella infection risk from domestic hot water.

Authors:  Paola Borella; M Teresa Montagna; Vincenzo Romano-Spica; Serena Stampi; Giovanna Stancanelli; Maria Triassi; Rachele Neglia; Isabella Marchesi; Guglielmina Fantuzzi; Daniela Tatò; Christian Napoli; Gianluigi Quaranta; Patrizia Laurenti; Erica Leoni; Giovanna De Luca; Cristina Ossi; Matteo Moro; Gabriella Ribera D'Alcalà
Journal:  Emerg Infect Dis       Date:  2004-03       Impact factor: 6.883

7.  The impact of lactoferrin with different levels of metal saturation on the intestinal epithelial barrier function and mucosal inflammation.

Authors:  Grzegorz Majka; Grażyna Więcek; Małgorzata Śróttek; Klaudyna Śpiewak; Małgorzata Brindell; Joanna Koziel; Janusz Marcinkiewicz; Magdalena Strus
Journal:  Biometals       Date:  2016-10-18       Impact factor: 2.949
  7 in total

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