Literature DB >> 10829327

Does cannabis use encourage other forms of illicit drug use?

D M Fergusson1, L J Horwood.   

Abstract

AIMS: To examine the relationship between cannabis use in adolescence and the onset of other illicit drug use.
METHOD: Data were gathered over the course of a 21-year longitudinal study of a birth cohort of 1265 New Zealand children. Measures analysed included: (a) frequency of cannabis use and other illicit drugs from 15-21; (b) family, social, educational and behavioural backgrounds of cohort members prior to 15; and (c) adolescent life-style variables.
FINDINGS: (i) By 21, nearly 70% of cohort members and used cannabis and 26% had used other illicit drugs. (ii) In all but three cases, the use of cannabis had preceded the use of illicit drugs. (iii) Those using cannabis on more than 50 occasions a year had hazards of other illicit drug use that were 140 times higher than non-users. (iv) After adjustment for covariate factors, including childhood factors, family factors and adolescent life-style factors, cannabis use remained strongly related to the onset of other forms of illicit drug use. Those using cannabis on more than 50 occasions per year had hazards of other illicit drug use that were 59.2 times higher than non-users.
CONCLUSIONS: Findings support the view that cannabis may act as a gateway drug that encourages other forms of illicit drug use. None the less, the possibility remains that the association is non-causal and reflects factors that were not adequately controlled in the analysis.

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Year:  2000        PMID: 10829327     DOI: 10.1046/j.1360-0443.2000.9545053.x

Source DB:  PubMed          Journal:  Addiction        ISSN: 0965-2140            Impact factor:   6.526


  56 in total

1.  Cannabis and mental health.

Authors:  Joseph M Rey; Christopher C Tennant
Journal:  BMJ       Date:  2002-11-23

2.  Gene-environment interplay in affect and dementia: emotional modulation of cognitive expression in personal outcomes.

Authors:  T Palomo; R J Beninger; R M Kostrzewa; T Archer
Journal:  Neurotox Res       Date:  2004       Impact factor: 3.911

3.  Psychiatric Symptoms, Salivary Cortisol and Cytokine Levels in Young Marijuana Users.

Authors:  Christine C Cloak; Daniel Alicata; Thomas M Ernst; Linda Chang
Journal:  J Neuroimmune Pharmacol       Date:  2015-04-15       Impact factor: 4.147

4.  Ecstasy and gateway drugs: initiating the use of ecstasy and other drugs.

Authors:  Lesley W Reid; Kirk W Elifson; Claire E Sterk
Journal:  Ann Epidemiol       Date:  2006-11-29       Impact factor: 3.797

5.  Do adolescent ecstasy users have different attitudes towards drugs when compared to marijuana users?

Authors:  Silvia S Martins; Carla L Storr; Pierre K Alexandre; Howard D Chilcoat
Journal:  Drug Alcohol Depend       Date:  2007-12-18       Impact factor: 4.492

6.  Contributions of ethnicity to differential item functioning of cannabis abuse and dependence symptoms.

Authors:  Ian R Gizer; David A Gilder; Philip Lau; Ting Wang; Kirk C Wilhelmsen; Cindy L Ehlers
Journal:  J Stud Alcohol Drugs       Date:  2013-03       Impact factor: 2.582

Review 7.  Cannabis controversies: how genetics can inform the study of comorbidity.

Authors:  Arpana Agrawal; Michael T Lynskey
Journal:  Addiction       Date:  2014-01-19       Impact factor: 6.526

Review 8.  Alcohol use disorders in adolescents: epidemiology, diagnosis, psychosocial interventions, and pharmacological treatment.

Authors:  Duncan B Clark; Oscar Bukstein; Jack Cornelius
Journal:  Paediatr Drugs       Date:  2002       Impact factor: 3.022

9.  Childhood determinants of adult psychiatric disorder.

Authors:  Tom Fryers; Traolach Brugha
Journal:  Clin Pract Epidemiol Ment Health       Date:  2013-02-22

Review 10.  Role of endocannabinoid system in mental diseases.

Authors:  Jorge Manzanares; Leyre Urigüen; Gabriel Rubio; Tomás Palomo
Journal:  Neurotox Res       Date:  2004       Impact factor: 3.911

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