Literature DB >> 10828332

Three-dimensional numerical simulations of flow through a stenosed coronary bypass.

C Bertolotti1, V Deplano.   

Abstract

This work analyzes the flow patterns at the anastomosis of a stenosed coronary bypass. Three-dimensional numerical simulations are performed using a finite elements method. We consider a geometrical model of the host coronary artery with and without a 75% severity stenosis for three different locations from the anastomosis. The flow features - velocity profiles, secondary motions and wall shear stresses - are compared for different configurations of the flow rate and of the distance of the anastomosis from the site of occlusion (called distance of grafting). The combination of the junction flow effects - counter rotating vortices - with the stenosis effects - confined jet flow - is particularly important when the distance of grafting is short. Given that the residual flow issued from the pathologic stenosis being non-negligible after two weeks grafting, models without stenosis cannot predict the evolution of the wall shear stress in the vicinity of the anastomosis.

Mesh:

Year:  2000        PMID: 10828332     DOI: 10.1016/s0021-9290(00)00012-9

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  5 in total

1.  Numerical Simulation of Physiological Blood Flow in 2-way Coronary Artery Bypass Grafts.

Authors:  Aike Qiao; Youjun Liu; Siyang Li; Hu Zhao
Journal:  J Biol Phys       Date:  2005-05       Impact factor: 1.365

2.  Numerical simulations of unsteady flows in a stenosed coronary bypass graft.

Authors:  V Deplano; C Bertolotti; O Boiron
Journal:  Med Biol Eng Comput       Date:  2001-07       Impact factor: 3.079

Review 3.  Coronary artery bypass grafting hemodynamics and anastomosis design: a biomedical engineering review.

Authors:  Dhanjoo N Ghista; Foad Kabinejadian
Journal:  Biomed Eng Online       Date:  2013-12-13       Impact factor: 2.819

4.  Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts.

Authors:  Thomas Frauenfelder; Evangelos Boutsianis; Thomas Schertler; Lars Husmann; Sebastian Leschka; Dimos Poulikakos; Borut Marincek; Hatem Alkadhi
Journal:  Biomed Eng Online       Date:  2007-09-26       Impact factor: 2.819

5.  Computational model of blood flow in the aorto-coronary bypass graft.

Authors:  Meena Sankaranarayanan; Leok Poh Chua; Dhanjoo N Ghista; Yong Seng Tan
Journal:  Biomed Eng Online       Date:  2005-03-04       Impact factor: 2.819

  5 in total

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