Literature DB >> 10827452

Forward with BACs: new tools for herpesvirus genomics.

W Brune1, M Messerle, U H Koszinowski.   

Abstract

The large, complex genomes of herpesviruses document the high degree of adaptation of these viruses to their hosts. Not surprisingly, the methods developed over the past 30 years to analyse herpesvirus genomes have paralleled those used to investigate the genetics of eukaryotic cells. The recent use of bacterial artificial chromosome (BAC) technology in herpesvirus genetics has made their genomes accessible to the tools of bacterial genetics. This has opened up new avenues for reverse and forward genetics of this virus family in basic research, and also for vector and vaccine development.

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Year:  2000        PMID： 10827452     DOI： 10.1016/s0168-9525(00)02015-1

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  44 in total

1.  Virus reconstituted from infectious bacterial artificial chromosome (BAC)-cloned murine gammaherpesvirus 68 acquires wild-type properties in vivo only after excision of BAC vector sequences.

Authors:  H Adler; M Messerle; U H Koszinowski
Journal:  J Virol       Date:  2001-06       Impact factor: 5.103

2.  Cloning of the full-length rhesus cytomegalovirus genome as an infectious and self-excisable bacterial artificial chromosome for analysis of viral pathogenesis.

Authors:  W L William Chang; Peter A Barry
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

3.  SUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replication.

Authors:  Michael Nevels; Wolfram Brune; Thomas Shenk
Journal:  J Virol       Date:  2004-07       Impact factor: 5.103

4.  Application of a bacterial artificial chromosome modification system for a human artificial chromosome vector.

Authors:  Shigeyuki Yamaguchi; Ryosuke Niwa; Yasuhiro Kazuki; Tetsuya Ohbayashi
Journal:  Yonago Acta Med       Date:  2011-03-01       Impact factor: 1.641

5.  Transposon-assisted cloning and traceless mutagenesis of adenoviruses: Development of a novel vector based on species D.

Authors:  Zsolt Ruzsics; Markus Wagner; Andrea Osterlehner; Jonathan Cook; Ulrich Koszinowski; Hans-Gerhard Burgert
Journal:  J Virol       Date:  2006-08       Impact factor: 5.103

6.  Methods for Studying the Function of Cytomegalovirus GPCRs.

Authors:  Christine M O'Connor; William E Miller
Journal:  Methods Mol Biol       Date:  2021

Review 7.  Herpesviral vectors and their application in oncolytic therapy, vaccination, and gene transfer.

Authors:  Susanne M Bailer; Christina Funk; André Riedl; Zsolt Ruzsics
Journal:  Virus Genes       Date:  2017-06-20       Impact factor: 2.332

8.  Genetic evidence of an essential role for cytomegalovirus small capsid protein in viral growth.

Authors:  E M Borst; S Mathys; M Wagner; W Muranyi; M Messerle
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

9.  Developing a Vaccine against Congenital Cytomegalovirus (CMV) Infection: What Have We Learned from Animal Models? Where Should We Go Next?

Authors:  Mark R Schleiss
Journal:  Future Virol       Date:  2013-12       Impact factor: 1.831

10.  Red-mediated transposition and final release of the mini-F vector of a cloned infectious herpesvirus genome.

Authors:  Felix Wussow; Helmut Fickenscher; B Karsten Tischer
Journal:  PLoS One       Date:  2009-12-04       Impact factor: 3.240
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