Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Herpesviral vectors and their application in oncolytic therapy, vaccination, and gene transfer.

Literature DB >> 28634751

Herpesviral vectors and their application in oncolytic therapy, vaccination, and gene transfer.

Susanne M Bailer^1,2, Christina Funk^3,4, André Riedl^5,6, Zsolt Ruzsics^7,8.

Abstract

Herpesviruses are enveloped DNA viruses that infect vertebrate cells. Their high potential cloning capacity and the lifelong persistence of their genomes in various host cells make them attractive platforms for vector-based therapy. In this review, we would like to highlight recent advances of three major areas of herpesvirus vector development and application: (i) oncolytic therapy, (ii) recombinant vaccines, and (iii) large capacity gene transfer vehicles.

Entities: Species

Keywords: BAC technology; Gene transfer; Herpesviral vectors; High-capacity cloning; Oncolytic therapy; Vaccination

Mesh：

Substances：
Vaccines, Synthetic

Year: 2017 PMID： 28634751 DOI： 10.1007/s11262-017-1482-7

Source DB: PubMed Journal: Virus Genes ISSN： 0920-8569 Impact factor: 2.332

58 in total

1. Genetic design of an optimized packaging cell line for gene vectors transducing human B cells.

Authors: E Hettich; A Janz; R Zeidler; D Pich; E Hellebrand; B Weissflog; A Moosmann; W Hammerschmidt
Journal: Gene Ther Date: 2006-05 Impact factor: 5.250

Review 2. Oncolytic viruses: From bench to bedside with a focus on safety.

Authors: Pascal R A Buijs; Judith H E Verhagen; Casper H J van Eijck; Bernadette G van den Hoogen
Journal: Hum Vaccin Immunother Date: 2015 Impact factor: 3.452

3. Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus, an alphaherpesvirus.

Authors: G A Smith; L W Enquist
Journal: J Virol Date: 1999-08 Impact factor: 5.103

Review 4. Going viral with cancer immunotherapy.

Authors: Brian D Lichty; Caroline J Breitbach; David F Stojdl; John C Bell
Journal: Nat Rev Cancer Date: 2014-07-03 Impact factor: 60.716

Review 5. The biochemistry and mechanism of action of acyclovir.

Authors: G B Elion
Journal: J Antimicrob Chemother Date: 1983-09 Impact factor: 5.790

6. Immune clearance of highly pathogenic SIV infection.

Authors: Scott G Hansen; Michael Piatak; Abigail B Ventura; Colette M Hughes; Roxanne M Gilbride; Julia C Ford; Kelli Oswald; Rebecca Shoemaker; Yuan Li; Matthew S Lewis; Awbrey N Gilliam; Guangwu Xu; Nathan Whizin; Benjamin J Burwitz; Shannon L Planer; John M Turner; Alfred W Legasse; Michael K Axthelm; Jay A Nelson; Klaus Früh; Jonah B Sacha; Jacob D Estes; Brandon F Keele; Paul T Edlefsen; Jeffrey D Lifson; Louis J Picker
Journal: Nature Date: 2013-09-11 Impact factor: 49.962

7. The infectious BAC genomic DNA expression library: a high capacity vector system for functional genomics.

Authors: Michele M P Lufino; Pauline A H Edser; Michael A Quail; Stephen Rice; David J Adams; Richard Wade-Martins
Journal: Sci Rep Date: 2016-06-29 Impact factor: 4.379

8. Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins.

Authors: Biljana Petrovic; Tatiana Gianni; Valentina Gatta; Gabriella Campadelli-Fiume
Journal: PLoS Pathog Date: 2017-04-19 Impact factor: 6.823

Herpesviral vectors and their application in oncolytic therapy, vaccination, and gene transfer.

1. Genetic design of an optimized packaging cell line for gene vectors transducing human B cells.

Review 2. Oncolytic viruses: From bench to bedside with a focus on safety.

3. Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus, an alphaherpesvirus.

Review 4. Going viral with cancer immunotherapy.

Review 5. The biochemistry and mechanism of action of acyclovir.

6. Immune clearance of highly pathogenic SIV infection.

7. The infectious BAC genomic DNA expression library: a high capacity vector system for functional genomics.

8. Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins.

9. A Diverse Repertoire of CD4 T Cells Targets the Immediate-Early 1 Protein of Human Cytomegalovirus.

Review 10. Oncolytic virotherapy using herpes simplex virus: how far have we come?

1. From Virus to vector to medicine: Foreword by guest editors.

Review 2. Viruses as tools in gene therapy, vaccine development, and cancer treatment.