Literature DB >> 10825998

A two-step total synthesis of the natural pentacycle trichodimerol, a novel inhibitor of TNF-alpha production.

D Barnes-Seeman1, E J Corey.   

Abstract

[formula: see text] Trichodimerol (1) can be synthesized by a remarkable dimerization of the chiral hydroxy dienone 5.

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Year:  1999        PMID： 10825998     DOI： 10.1021/ol991070h

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  11 in total

Review 1.  The essence of total synthesis.

Authors:  K C Nicolaou; Scott A Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-09       Impact factor: 11.205

Review 2.  Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors:  K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal:  Chem Soc Rev       Date:  2012-06-28       Impact factor: 54.564

3.  Total synthesis of atrochamins F, H, I, and J through cascade reactions.

Authors:  K C Nicolaou; Troy Lister; Ross M Denton; Christine F Gelin
Journal:  Tetrahedron       Date:  2008-05-19       Impact factor: 2.457

4.  Synthesis of (+/-)-epoxysorbicillinol using a novel cyclohexa-2,5-dienone with synthetic applications to other sorbicillin derivatives.

Authors:  L H Pettus; R W Van De Water; T R Pettus
Journal:  Org Lett       Date:  2001-03-22       Impact factor: 6.005

Review 5.  Dearomatization strategies in the synthesis of complex natural products.

Authors:  Stéphane P Roche; John A Porco
Journal:  Angew Chem Int Ed Engl       Date:  2011-04-19       Impact factor: 15.336

6.  A synthesis of the carbon skeleton of maoecrystal V.

Authors:  Paul J Krawczuk; Niklas Schöne; Phil S Baran
Journal:  Org Lett       Date:  2009-11-05       Impact factor: 6.005

7.  A strategy for complex dimer formation when biomimicry fails: total synthesis of ten coccinellid alkaloids.

Authors:  Trevor C Sherwood; Adam H Trotta; Scott A Snyder
Journal:  J Am Chem Soc       Date:  2014-06-24       Impact factor: 15.419

8.  Biocatalytic site- and enantioselective oxidative dearomatization of phenols.

Authors:  Summer A Baker Dockrey; April L Lukowski; Marc R Becker; Alison R H Narayan
Journal:  Nat Chem       Date:  2017-11-13       Impact factor: 24.427

9.  Total synthesis and stereochemical assignment of (±)-sorbiterrin A.

Authors:  Chao Qi; Tian Qin; Daisuke Suzuki; John A Porco
Journal:  J Am Chem Soc       Date:  2014-02-24       Impact factor: 15.419

10.  Diels-Alder Reactions During the Biosynthesis of Sorbicillinoids.

Authors:  Lukas Kahlert; Eman F Bassiony; Russell J Cox; Elizabeth J Skellam
Journal:  Angew Chem Int Ed Engl       Date:  2020-02-04       Impact factor: 15.336
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