Literature DB >> 10822223

From guidelines to hospital practice: reducing inappropriate ordering of thyroid hormone and antibody tests.

M E Toubert1, S Chevret, B Cassinat, M H Schlageter, J P Beressi, J D Rain.   

Abstract

OBJECTIVE: Because of major technical improvements and conscious care about cost effectiveness, limiting the inadequate use of thyroid biological tests appears to be a major issue.
DESIGN: To (i) estimate the ordering prevalence of each thyroid test, (ii) assess the prevalence of relevant thyroid tests, and (iii) evaluate the impact of expressing justification for tests during a 2-month intervention period on these prevalences.
METHODS: During a prospective 2-month survey (June-July 1997), all the request forms were divided into four groups of prescription: (1) investigation of thyroid function, (2) taking drugs affecting the thyroid, (3) monitoring of nodule and cancer, and (4) investigation of thyroid autoimmunity. Their appropriateness was thus determined according to consensus in our hospital and previously published recommendations. Results were compared with those of retrospective similar 2-month periods in 1996 and 1998. Combinations of thyroid function tests and thyroid antibodies were analyzed during the 1996, 1997 and 1998 periods.
RESULTS: The overall estimated rate of appropriate ordering between 1996 and 1997 increased from 42.5% to 72.4% (P<10(-4)), with a significant improvement in each group of main diagnosis referral, except in group 3 where suitability was always over 85%. However, in group 4, appropriateness remained low (36%). Combinations of thyroid tests revealed an increase in single TSH order forms and single autoantibodies to thyroperoxidase (TPOAb) ones, while TSH+free thyroxine+free tri-iodothyronine and TPOAb+ autoantibodies to thyroglobulin ones decreased significantly. Interestingly, all these changes were maintained 1 year later (June-July 1998) even though physicians were not aware of this new study.
CONCLUSIONS: Persistent change in medical practice was thus assessed.

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Year:  2000        PMID: 10822223     DOI: 10.1530/eje.0.1420605

Source DB:  PubMed          Journal:  Eur J Endocrinol        ISSN: 0804-4643            Impact factor:   6.664


  8 in total

1.  GAUGING THE EXTENT OF THYROIDECTOMY FOR INDETERMINATE THYROID NODULES: AN ONCOLOGIC PERSPECTIVE.

Authors:  David F Schneider; Linda M Cherney Stafford; Nicole Brys; Caprice C Greenberg; Courtney J Balentine; Dawn M Elfenbein; Susan C Pitt
Journal:  Endocr Pract       Date:  2017-01-17       Impact factor: 3.443

2.  Are we using Thyroid Function Tests Appropriately?

Authors:  Shalini Gupta; Minni Verma; Ashwani Kumar Gupta; Amandeep Kaur; Vaneet Kaur; Kamaljit Singh
Journal:  Indian J Clin Biochem       Date:  2011-04-07

3.  The Diagnostic Yield of Thyroid Function Tests and their Cost-effectiveness in the Student Clinic at Sultan Qaboos University: Retrospective chart review.

Authors:  Kawther El Shafie; Asila Al-Shaqsi; Badriya Al-Mahrouqi; Hadia Al Lawati; Shyam S Ganguly; Samir Al Adawi; Mohammed Al Shafaee
Journal:  Sultan Qaboos Univ Med J       Date:  2010-07-19

4.  Initial evaluation of thyroid dysfunction - Are simultaneous TSH and fT4 tests necessary?

Authors:  Claudio Schneider; Martin Feller; Douglas C Bauer; Tinh-Hai Collet; Bruno R da Costa; Reto Auer; Robin P Peeters; Suzanne J Brown; Alexandra P Bremner; Peter C O'Leary; Peter Feddema; Peter J Leedman; Drahomir Aujesky; John P Walsh; Nicolas Rodondi
Journal:  PLoS One       Date:  2018-04-30       Impact factor: 3.240

Review 5.  Reducing Test Utilization in Hospital Settings: A Narrative Review.

Authors:  Renuka S Bindraban; Maarten J Ten Berg; Christiana A Naaktgeboren; Mark H H Kramer; Wouter W Van Solinge; Prabath W B Nanayakkara
Journal:  Ann Lab Med       Date:  2018-09       Impact factor: 3.464

6.  Reducing test request for anti-thyroglobulin and anti-thyroid peroxidase antibodies: trends before and after interventions based on rejection rules and profile management.

Authors:  Pedro Sánchez Pellicer; Ruth González Tamayo; Vicente Navarro López
Journal:  Biochem Med (Zagreb)       Date:  2018-10-15       Impact factor: 2.313

Review 7.  Effectiveness of interventions to reduce ordering of thyroid function tests: a systematic review.

Authors:  Zhivko Zhelev; Rebecca Abbott; Morwenna Rogers; Simon Fleming; Anthea Patterson; William Trevor Hamilton; Janet Heaton; Jo Thompson Coon; Bijay Vaidya; Christopher Hyde
Journal:  BMJ Open       Date:  2016-06-03       Impact factor: 2.692

8.  Thyroid Hormone Tests Ordering Practice and Cost-Effectiveness in Samples Referred to International Clinical Laboratories from Addis Ababa Health Facilities.

Authors:  Kifle Tilahun; Meaza Demissie; Tamrat Bekele; Mesfin Nigussie; Damen H/Mariam
Journal:  Ethiop J Health Sci       Date:  2020-05
  8 in total

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