Literature DB >> 22468046

Are we using Thyroid Function Tests Appropriately?

Shalini Gupta, Minni Verma, Ashwani Kumar Gupta, Amandeep Kaur, Vaneet Kaur, Kamaljit Singh.   

Abstract

Thyroid function tests are very important for the diagnosis and monitoring of patients with thyroid dysfunction. The guidelines recommend serum thyroid stimulating hormone (TSH) as the single most reliable test to diagnose all common forms of hypothyroidism and hyperthyroidism. The aim of this study was to analyze the ordering pattern for thyroid function tests by physicians and the analysis of results based on the clinical history. The mean age of the patients was 32.5 ± 6.5 years. Majority of samples (87.7% of total) were received from the departments of Medicine and Gynae. Thyroid profiles (47.5%) were ordered more frequently as compared to TSH only (46%). There was no significant difference in the percentage of normal reports for both types of tests. 77.8% of TFT and 76.6% of TSH samples had results within the reference range. The percentage of abnormal results was 13.7% in the patients who were screened for thyroid disorders. There is a need to redefine the case definition for thyroid dysfunction and order the appropriate test in a rational and cost effective manner.

Entities:  

Keywords:  Hyperthyroidism; Hypothyroidism; TSH; Thyroid function test

Year:  2011        PMID: 22468046      PMCID: PMC3107420          DOI: 10.1007/s12291-011-0128-0

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN: 0970-1915


  19 in total

1.  Cases referred for tests of thyroid function disorders at a tertiary care teaching hospital of Bihar: some experience.

Authors:  S Roy; A Bhattacharjee; A Mukherjee; D Jaisawal; S N Das; R Pal
Journal:  Indian J Public Health       Date:  2006 Oct-Dec

2.  An analysis of cases referred for thyroid function disorder in a teaching hospital of Calcutta.

Authors:  S Chauduri; A Roy; A Mukhergee; A B Biswas
Journal:  Indian J Public Health       Date:  1996 Apr-Jun

Review 3.  Biochemical testing of thyroid function.

Authors:  G G Klee; I D Hay
Journal:  Endocrinol Metab Clin North Am       Date:  1997-12       Impact factor: 4.741

4.  Subclinical hypothyroidism.

Authors:  D S Cooper
Journal:  JAMA       Date:  1987-07-10       Impact factor: 56.272

5.  Optimal use of blood tests for assessment of thyroid function.

Authors:  D V Becker; S T Bigos; E Gaitan; J C Morris; M L Rallison; C A Spencer; M Sugawara; L Van Middlesworth; L Wartofsky
Journal:  JAMA       Date:  1993-06-02       Impact factor: 56.272

6.  American Thyroid Association guidelines for detection of thyroid dysfunction.

Authors:  P W Ladenson; P A Singer; K B Ain; N Bagchi; S T Bigos; E G Levy; S A Smith; G H Daniels; H D Cohen
Journal:  Arch Intern Med       Date:  2000-06-12

7.  The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey.

Authors:  M P Vanderpump; W M Tunbridge; J M French; D Appleton; D Bates; F Clark; J Grimley Evans; D M Hasan; H Rodgers; F Tunbridge
Journal:  Clin Endocrinol (Oxf)       Date:  1995-07       Impact factor: 3.478

8.  Prospective study of the spontaneous course of subclinical hypothyroidism: prognostic value of thyrotropin, thyroid reserve, and thyroid antibodies.

Authors:  Gerold Huber; Jean-Jacques Staub; Christian Meier; Cristina Mitrache; Merih Guglielmetti; Peter Huber; Lewis E Braverman
Journal:  J Clin Endocrinol Metab       Date:  2002-07       Impact factor: 5.958

9.  Diagnostic strategies for subclinical hypothyroidism.

Authors:  Shruti Mohanty; W Amruthlal; G C Reddy; G Kusumanjali; A S Kanagasabapathy; Pragna Rao
Journal:  Indian J Clin Biochem       Date:  2008-10-01

10.  Treatment guidelines for patients with hyperthyroidism and hypothyroidism. Standards of Care Committee, American Thyroid Association.

Authors:  P A Singer; D S Cooper; E G Levy; P W Ladenson; L E Braverman; G Daniels; F S Greenspan; I R McDougall; T F Nikolai
Journal:  JAMA       Date:  1995-03-08       Impact factor: 56.272

View more
  5 in total

1.  Investigating Investigation (Ab)Use: Thyroid Function Test Audit in a Tertiary Care Teaching Institute in Eastern India.

Authors:  Suchanda Sahu; Joseph John
Journal:  Indian J Clin Biochem       Date:  2021-01-15

2.  Use of Electronic Clinical Decision Support and Hard Stops to Decrease Unnecessary Thyroid Function Testing.

Authors:  Sonia Dalal; Siddharth Bhesania; Steven Silber; Parag Mehta
Journal:  BMJ Qual Improv Rep       Date:  2017-04-28

3.  Primary care use of laboratory tests in Northern Ireland's Western Health and Social Care Trust: a cross-sectional study.

Authors:  Magda Bucholc; Maurice O'Kane; Ciaran Mullan; Siobhan Ashe; Liam Maguire
Journal:  BMJ Open       Date:  2019-06-21       Impact factor: 2.692

4.  Thyroid Hormone Tests Ordering Practice and Cost-Effectiveness in Samples Referred to International Clinical Laboratories from Addis Ababa Health Facilities.

Authors:  Kifle Tilahun; Meaza Demissie; Tamrat Bekele; Mesfin Nigussie; Damen H/Mariam
Journal:  Ethiop J Health Sci       Date:  2020-05

5.  Cystatin C, a Controversial Biomarker in Hypothyroid Patients under Levothyroxine Therapy: THYRenal, a Pilot Cohort Observational Study.

Authors:  Marta Greco; Daniela Patrizia Foti; Antonio Aversa; Giorgio Fuiano; Antonio Brunetti; Mariadelina Simeoni
Journal:  J Clin Med       Date:  2020-09-13       Impact factor: 4.241

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.