Literature DB >> 10814095

Amphidinolide T, novel 19-membered macrolide from marine dinoflagellate Amphidinium sp.

M Tsuda1, T Endo, J Kobayashi.   

Abstract

A novel 19-membered macrolide, amphidinolide T (1), has been isolated from a marine dinoflagellate Amphidinium sp., and the structure was elucidated on the basis of spectroscopic data. Relative stereochemistry at C-7, C-8, and C-10 was deduced from the NOESY correlations, while absolute configurations at C-2, C-13, C-14, and C-18 were assigned on the basis of NMR data of the MTPA esters of 1 and those of degradation products of 1.

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Year:  2000        PMID: 10814095     DOI: 10.1021/jo991393r

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  7 in total

1.  A formal synthesis of the C1-C9 fragment of amphidinolide C employing the Tamaru reaction.

Authors:  Mahesh P Paudyal; Nigam P Rath; Christopher D Spilling
Journal:  Org Lett       Date:  2010-07-02       Impact factor: 6.005

Review 2.  The biosynthesis of polyketide metabolites by dinoflagellates.

Authors:  Kathleen S Rein; Richard V Snyder
Journal:  Adv Appl Microbiol       Date:  2006       Impact factor: 5.086

3.  Total syntheses of amphidinolides T1 and T4 via catalytic, stereoselective, reductive macrocyclizations.

Authors:  Elizabeth A Colby; Karen C O'Brien; Timothy F Jamison
Journal:  J Am Chem Soc       Date:  2005-03-30       Impact factor: 15.419

4.  Iriomoteolides-9a and 11a: two new odd-numbered macrolides from the marine dinoflagellate Amphidinium species.

Authors:  Keiko Kumagai; Masayuki Tsuda; Eri Fukushi; Jun Kawabata; Atsunori Masuda; Masashi Tsuda
Journal:  J Nat Med       Date:  2017-03-02       Impact factor: 2.343

5.  Antibacterial Activity and Amphidinol Profiling of the Marine Dinoflagellate Amphidinium carterae (Subclade III).

Authors:  Maria Elena Barone; Elliot Murphy; Rachel Parkes; Gerard T A Fleming; Floriana Campanile; Olivier P Thomas; Nicolas Touzet
Journal:  Int J Mol Sci       Date:  2021-11-11       Impact factor: 5.923

Review 6.  The Tetrahydrofuran Motif in Polyketide Marine Drugs.

Authors:  Laura Fernández-Peña; Carlos Díez-Poza; Paula González-Andrés; Asunción Barbero
Journal:  Mar Drugs       Date:  2022-02-03       Impact factor: 5.118

Review 7.  Marine-Derived Macrolides 1990-2020: An Overview of Chemical and Biological Diversity.

Authors:  Hairong Zhang; Jiabin Zou; Xiaoxue Yan; Junlong Chen; Xiujiao Cao; Jialing Wu; Yinghui Liu; Tingting Wang
Journal:  Mar Drugs       Date:  2021-03-25       Impact factor: 5.118

  7 in total

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