Literature DB >> 108130

Effects of increasing Mg++ ion concentration on the PKU monitoring assay.

K J Brown, R B Elliott, D R Lines.   

Abstract

Inaccuracies in a commonly used bacterial inhibition assay for blood phenylalanine levels arise when the Mg++ ion concentration in the assay medium is increased. This has practical implications in the diagnosis and management of phenylketonuria.

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Year:  1979        PMID: 108130     DOI: 10.1007/bf01922707

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  6 in total

1.  A SIMPLE PHENYLALANINE METHOD FOR DETECTING PHENYLKETONURIA IN LARGE POPULATIONS OF NEWBORN INFANTS.

Authors:  R GUTHRIE; A SUSI
Journal:  Pediatrics       Date:  1963-09       Impact factor: 7.124

2.  Minimal media for quantitative studies with Bacillus subtilis.

Authors:  A L DEMAIN
Journal:  J Bacteriol       Date:  1958-05       Impact factor: 3.490

3.  Mutants of Escherichia coli requiring methionine or vitamin B12.

Authors:  B D DAVIS; E S MINGIOLI
Journal:  J Bacteriol       Date:  1950-07       Impact factor: 3.490

Review 4.  Phenylketonuria and its variations. A review of recent developments.

Authors:  M E Blaskovics; T L Nelson
Journal:  Calif Med       Date:  1971-07

5.  Differentiation of pathogenic, gram-negative, bacterial genera in the presence of beta-2-thienylalanine.

Authors:  K J Brown; D R Lines
Journal:  Can J Microbiol       Date:  1976-12       Impact factor: 2.419

6.  Effects of changes in Mg++ ion concentration upon bacterial inhibition by beta-2-thienylalanine in defined media.

Authors:  K J Brown; D R Lines
Journal:  Aust J Exp Biol Med Sci       Date:  1978-08
  6 in total
  3 in total

1.  False positive result of Guthrie inhibition assay for histidinaemia in a patient with phenylketonuria.

Authors:  N Sakura; N Kawahara; M Tanabe; T Miura; K Kanamori; A Yoshino; H Ohtake
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

2.  Colonization by Salmonella typhimurium and Shigella flexneri III of the gastrointestinal tract of mice treated with beta-2-thienylalanine and streptomycin.

Authors:  K J Brown; G W Tannock; R A Eyres; R B Elliott; D R Lines
Journal:  Antonie Van Leeuwenhoek       Date:  1979       Impact factor: 2.271

3.  The assay on a defined medium of the effects of beta-2-thienylalanine on the growth of anaerobic bacterial isolates from phenylketonuric patients.

Authors:  K J Brown; B V Vesey; G W Tannock; E B Bell; D R Lines; R B Elliott
Journal:  Med Microbiol Immunol       Date:  1980-02       Impact factor: 3.402

  3 in total

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