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Literature DB >> 1081022

Increased proliferation of T lymphocytes in the blood of patients with Hodgkin's disease.

C Huber, G Michlmayr, M Falkensamer, U Fink, G Zur Nedden, H Braunsteiner, H Huber.

Abstract

We investigated the number of DNA-synthesizing T lymphocytes in the blood of patients with Hodgkin's disease, with infectious mononucleosis and in normal controls. T cells were characterized by their ability to form rosettes with unsensitized neuramidase-treated sheep red blood cells. Cells in DNA synthesis were evaluated autoradiographically after in vitro incubation with [3H]thymidine. Our results indicated a preferential proliferation of T lymphocytes in the blood of patients with Hodgkin's disease and infectious mononucleosis and suggested an increased turnover of these cells.

Entities: Chemical Disease Species

Mesh：

Year: 1975 PMID： 1081022 PMCID： PMC1538248

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

19 in total

1. [T-lymphocytes in the peripheral blood and lymph nodes in lymphatic system diseases].

Authors: G Michlmayr; C Huber; U Fink; M Falkensammer; H Huber
Journal: Schweiz Med Wochenschr Date: 1974-06-08

2. Pathogenesis of Hodgkin's disease.

Authors: S E Order; S Hellman
Journal: Lancet Date: 1972-03-11 Impact factor: 79.321

3. Circulating lymphoid cells in Hodgkin's disease.

Authors: G H Fairley
Journal: Natl Cancer Inst Monogr Date: 1973-05

4. [Differentiation of human blood lymphocytes using serologic and autoradiographic methods. II. Results in primary and symptomatic immunoglobulin deficiency conditions (author's transl)].

Authors: C Huber; R Kurz; H Asamer; H Huber; H Braunsteiner
Journal: Klin Wochenschr Date: 1974-02-01

5. Kinetics of lymphocytes in Hodgkin's disease.

Authors: P Schick; F Trepel; H Theml; S Benedek; P Trumpp; W Kaboth; H Begemann; T M Fliedner
Journal: Blut Date: 1973-10

6. Significance of the changes in the circulating lymphoid cells in Hodgkin's disease.

Authors: D Cowther; G H Fairley; R L Sewell
Journal: Br Med J Date: 1969-05-24

7. [Cytological immunoglobulin determination in DNA synthetizing blood lymphocytes of patients with virus infections].

Authors: C Huber; H Asamer; R Kurz; H Huber; H Braunsteiner
Journal: Acta Haematol Date: 1971 Impact factor: 2.195

8. [DNA-synthesis in blood lymphocytes in malignant lymphogranuloma].

Authors: C Huber; H Huber; F Schmalzl; B Lederer; D Bütterich; H Braunsteiner
Journal: Acta Haematol Date: 1970 Impact factor: 2.195

9. Lymphoid cellular responses in the blood after immunization in man.

Authors: D Crowther; G H Fairley; R L Sewell
Journal: J Exp Med Date: 1969-05-01 Impact factor: 14.307

10. Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells.

Authors: M Jondal; G Holm; H Wigzell
Journal: J Exp Med Date: 1972-08-01 Impact factor: 14.307

8 in total

Review 1. Immunological characterization of lymphoproliferative disorders by membrane markers.

Authors: H Huber; G Michlmayr; C Huber; M Falkensammer
Journal: Klin Wochenschr Date: 1976-08-01

2. Abnormalities of in vitro immunoglobulin synthesis by peripheral blood lymphocytes from untreated patients with Hodgkin's disease.

Authors: S Romagnani; G F Del Prete; E Maggi; G Bellesi; G Biti; P L Rossi Ferrini; M Ricci
Journal: J Clin Invest Date: 1983-05 Impact factor: 14.808

Increased proliferation of T lymphocytes in the blood of patients with Hodgkin's disease.

1. [T-lymphocytes in the peripheral blood and lymph nodes in lymphatic system diseases].

2. Pathogenesis of Hodgkin's disease.

3. Circulating lymphoid cells in Hodgkin's disease.

4. [Differentiation of human blood lymphocytes using serologic and autoradiographic methods. II. Results in primary and symptomatic immunoglobulin deficiency conditions (author's transl)].

5. Kinetics of lymphocytes in Hodgkin's disease.

6. Significance of the changes in the circulating lymphoid cells in Hodgkin's disease.

7. [Cytological immunoglobulin determination in DNA synthetizing blood lymphocytes of patients with virus infections].

8. [DNA-synthesis in blood lymphocytes in malignant lymphogranuloma].

9. Lymphoid cellular responses in the blood after immunization in man.

10. Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells.

Review 1. Immunological characterization of lymphoproliferative disorders by membrane markers.

2. Abnormalities of in vitro immunoglobulin synthesis by peripheral blood lymphocytes from untreated patients with Hodgkin's disease.

3. The Reed-Sternberg cell/lymphocyte interaction: ultrastructure and characteristics of binding.

4. Large granular lymphocytes: morphological and functional properties. I. Results in normals.

5. Spontaneous lymphocyte proliferation and depressed cellular immunity in Hodgkin's disease.

6. DNA-synthesizing T and non-T cells in chronic lymphocytic leukemia.

7. [Density distribution of human lymphocytes. I. Results of research on normal lymphoid tissue].

8. [Neopterin, a new biochemical marker for clinical assessment of cell-mediated immune response].