Literature DB >> 310327

DNA-synthesizing T and non-T cells in chronic lymphocytic leukemia.

J A van der Woerd- de Lange, J Döhrmann, C Huber, P Schick, K Rauert, H Begemann.   

Abstract

In 21 patients with chronic lymphocytic leukemia (CLL) and in 8 hematologically normal persons the number of DNA-synthesizing peripheral blood lymphocytes was investigated by autoradiographic techniques. The lymphocytes were differentiated by EN-rosette tests into T and non-T lymphoid cells. The results show a normal number of proliferating T lymphoid cells and an increased number of proliferating non-T lymphoid cells in clinical stages O-I. Stages III-IV demonstrate a significant increase of the proliferation rate of both T and non-T lymphoid cells. The possible pathogenetic factors and the prognostic value of these results are discussed.

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Year:  1978        PMID： 310327     DOI： 10.1007/bf01007867

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  18 in total

1.  Letter: Decrease of T lymphocytes during ageing.

Authors:  W Augener; G Cohnen; A Reuter; G Brittinger
Journal:  Lancet       Date:  1974-06-08       Impact factor: 79.321

2.  Isolation of normal T cells in chronic lymphatic leukaemia.

Authors:  J Wybran; S Chantler; H H Fudenberg
Journal:  Lancet       Date:  1973-01-20       Impact factor: 79.321

3.  Kinetics of lymphocytes in Hodgkin's disease.

Authors:  P Schick; F Trepel; H Theml; S Benedek; P Trumpp; W Kaboth; H Begemann; T M Fliedner
Journal:  Blut       Date:  1973-10

4.  In vitro leukocyte thymidine uptake in chronic lymphocytic leukemia.

Authors:  R Lopez-Sandoval; H Moayeri; J E Sokal
Journal:  Cancer Res       Date:  1974-01       Impact factor: 12.701

5.  [Rosette tests in lymphoproliferative diseases].

Authors:  G Michlmayr; C Pathouli; M Falkensammer; C Huber; H Huber; H Braunsteiner
Journal:  Schweiz Med Wochenschr       Date:  1976-06-05

6.  Clinical significance of T-cells in chronic lymphocytic leukaemia.

Authors:  D Catovsky; E Miliani; A Okos; D A Galton
Journal:  Lancet       Date:  1974-09-28       Impact factor: 79.321

7.  Letter: Age dependence of T lymphocytes.

Authors:  C Alexopoulos; P Babitis
Journal:  Lancet       Date:  1976-02-21       Impact factor: 79.321

8.  [DNA-synthesis in blood lymphocytes in malignant lymphogranuloma].

Authors:  C Huber; H Huber; F Schmalzl; B Lederer; D Bütterich; H Braunsteiner
Journal:  Acta Haematol       Date:  1970       Impact factor: 2.195

9.  Surface markers and other characteristics of the lymphocyte in chronic lymphocytic leukemia.

Authors:  Z Bentwich; A Polliack; S D Douglas
Journal:  Isr J Med Sci       Date:  1976 Apr-May

10.  Lymphoid cellular responses in the blood after immunization in man.

Authors:  D Crowther; G H Fairley; R L Sewell
Journal:  J Exp Med       Date:  1969-05-01       Impact factor: 14.307
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  5 in total

1.  DNA content of leukaemic cells in non-Hodgkin's lymphomas of low-grade malignancy. Flow-cytometric and morphological investigations with special regard to hyperploid cells.

Authors:  J Düllmann; U Wulfhekel; W A Linden; H P Beck; K Hausmann
Journal:  Blut       Date:  1980-12

2.  Relation between the activity of poly(A)polymerase and the levels of protein synthesis in the lymphocytes of patients with chronic lymphocytic leukemia.

Authors:  A Gounaris; N Courtis; G A Pangalis; C M Tsiapalis; T Trangas
Journal:  Blut       Date:  1988-11

3.  [Neopterin, a new biochemical marker for clinical assessment of cell-mediated immune response].

Authors:  C Huber; D Fuchs; D Niederwieser; A Hausen; G Reibnegger; K Nilsson; H Wachter
Journal:  Klin Wochenschr       Date:  1984-02-01

4.  DNA-synthesizing T and non-T cells in bacterial infections.

Authors:  J A van der Woerd-de Lange; N Omran; W Kaboth; F Heiss; H Begemann
Journal:  Blut       Date:  1980-02

5.  Protein synthesis in the blood lymphocytes of chronic lymphocytic leukemia and its relationship to prognosis.

Authors:  B Emmerich; R Pichlmeier; R Ristione; P Maubach; E Thiel; W E Berdel; K Ulm; U Fink; J Rastetter
Journal:  Klin Wochenschr       Date:  1982-08
  5 in total

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