Literature DB >> 108040

Circulating carcinoembryonic antigen immune complexes in sera of patients with carcinomata of the gastrointestinal tract.

K Kapsopoulou-Dominos, F A Anderer.   

Abstract

The sera of patients with histologically proven carcinomata of the gastrointestinal tract were fractionated by gel filtration and the fractions assayed for the presence of free carcinoembryonic antigen (CEA) binding immunoglobulins and CEA immune complexes by radioimmuno-double-diffusion, using 125I-CEA as a marker. In eleven out of thirteen cases with disease recurrence, the presence of CEA-IgM complexes was observed, and in three out of thirteen cases the presence of CEA-IgG complexes, could be demonstrated. Free CEA-binding immunoglobulins could not be detected.

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Year:  1979        PMID： 108040      PMCID： PMC1537644     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  14 in total

1.  Carcinoembryonic antigen-antibody complexes in a patient with colonic carcinoma and nephrotic syndrome.

Authors:  M E Costanza; V Pinn; R S Schwartz; L Nathanson
Journal:  N Engl J Med       Date:  1973-09-06       Impact factor: 91.245

2.  Blocking of lymphocyte-mediated cytotoxicity for rat hepatoma cells by tumour-specific antigen-antibody complexes.

Authors:  R W Baldwin; M R Price; R A Robins
Journal:  Nat New Biol       Date:  1972-08-09

3.  Molecular size of carcinoembryonic antigen in the plasma of patients with malignant disease.

Authors:  Q Pletsch; D M Goldenberg
Journal:  J Natl Cancer Inst       Date:  1974-11       Impact factor: 13.506

4.  Circulating immune complexes in human neuroblastoma: direct assay and role in blocking specific cellular immunity.

Authors:  D G Jose; R Seshadri
Journal:  Int J Cancer       Date:  1974-06-15       Impact factor: 7.396

5.  Human anti-CEA antibodies detected by radioimmunoelectrophoresis.

Authors:  J M Gold; S O Freedman; P Gold
Journal:  Nat New Biol       Date:  1972-09-13

6.  The blood group A-like site on the carcinoembryonic antigen.

Authors:  J M Gold; P Gold
Journal:  Cancer Res       Date:  1973-11       Impact factor: 12.701

7.  Absence of circulating antibodies to carcinoembryonic antigen in patients with gastrointestinal malignancies.

Authors:  P Lo Gerfo; F P Herter; S J Bennett
Journal:  Int J Cancer       Date:  1972-03-15       Impact factor: 7.396

8.  Further investigations of circulating antibodies in colon cancer patients: on the autoantigenicity of the carcinoembryonic antigen.

Authors:  E Collatz; S Von Kleist; P Burtin
Journal:  Int J Cancer       Date:  1971-09-15       Impact factor: 7.396

9.  The antigenicity of carcinoembryonic antigen in man.

Authors:  J M MacSween
Journal:  Int J Cancer       Date:  1975-02-15       Impact factor: 7.396

10.  DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.

Authors:  P GOLD; S O FREEDMAN
Journal:  J Exp Med       Date:  1965-03-01       Impact factor: 14.307
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  11 in total

Review 1.  Immune complexes in human diseases: a review.

Authors:  A N Theofilopoulos; F J Dixon
Journal:  Am J Pathol       Date:  1980-08       Impact factor: 4.307

2.  An approach to the routine estimation of circulating carcinoembryonic antigen immune complexes in patients with carcinomata of the gastrointestinal tract.

Authors:  K Kapsopoulou-Dominos; F A Anderer
Journal:  Clin Exp Immunol       Date:  1979-07       Impact factor: 4.330

3.  [Demonstration of circulating CEA or CEA-like antigens and immunoglobulin G containing immune complexes in colorectal carcinoma].

Authors:  R Pompecki
Journal:  Klin Wochenschr       Date:  1984-04-02

4.  Tumor-reactive IgE antibodies in plasma of patients with gastrointestinal carcinomas.

Authors:  I Berczi; V Holford-Strevens; Z H Warsi; L S McMorris; R H Thorlakson; T K Thorlakson; A H Sehon
Journal:  Cancer Immunol Immunother       Date:  1983       Impact factor: 6.968

5.  Nature of antigens and antibodies in immune complexes isolated by staphylococcal protein A from plasma of melanoma patients.

Authors:  R K Gupta; A M Leitch; D L Morton
Journal:  Cancer Immunol Immunother       Date:  1983       Impact factor: 6.968

6.  [Relapse prognosis for patients with adenocarcinoma of the gastrointestinal tract on the basis of carcinoembryonic antigen (CEA) and its circulating immune complexes (author's transl)].

Authors:  H J Staab; F A Anderer; E Stumpf; R Fischer
Journal:  Klin Wochenschr       Date:  1980-02-01

7.  Circulating immune complexes (CIC), carcinoembryonic antigen (CEA) and CIC containing CEA as markers for colorectal cancer.

Authors:  K A Chester; R H Begent
Journal:  Clin Exp Immunol       Date:  1984-12       Impact factor: 4.330

8.  CEA-containing immune complexes in sera of patients with colorectal and breast cancer--analysis of complexed immunoglobulin classes.

Authors:  C Fuchs; F Krapf; P Kern; S Hoferichter; W Jäger; J R Kalden
Journal:  Cancer Immunol Immunother       Date:  1988       Impact factor: 6.968

9.  Immune response to the carcinoembryonic antigen in patients treated with an anti-idiotype antibody vaccine.

Authors:  K A Foon; M Chakraborty; W J John; A Sherratt; H Köhler; M Bhattacharya-Chatterjee
Journal:  J Clin Invest       Date:  1995-07       Impact factor: 14.808

10.  Are circulating CEA immune complexes a prognostic marker in patients with carcinoma of the gastrointestinal tract?

Authors:  H J Staab; F A Anderer; E Stumpf; R Fischer
Journal:  Br J Cancer       Date:  1980-07       Impact factor: 7.640
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